Sprinkling salt on mitochondria: The metabolic and pathophysiological roles of mitochondrial Na+ signaling mediated by NCLX.
Sign Up to like & getrecommendations! Published in 2021 at "Cell calcium"
DOI: 10.1016/j.ceca.2021.102416
Abstract: NCLX, the mitochondrial Na+/Ca2+ transporter is a key player in Ca2+ signaling. However, its role in Na+ signaling is poorly understood. In this review we focus on Na+ signaling by NCLX, and discuss recent physiological… read more here.
Keywords: mitochondria metabolic; salt mitochondria; roles mitochondrial; pathophysiological roles ... See more keywords
Multiple pathophysiological roles of midkine in human disease.
Sign Up to like & getrecommendations! Published in 2020 at "Cytokine"
DOI: 10.1016/j.cyto.2020.155242
Abstract: Midkine (MK) is a low molecular-weight protein that was first identified as the product of a retinoic acid-responsive gene involved in embryonic development. Recent studies have indicated that MK levels are related to various diseases,… read more here.
Keywords: roles midkine; multiple pathophysiological; disease; pathophysiological roles ... See more keywords
Pathophysiological roles of integrins in gliomas from the perspective of glioma stem cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.962481
Abstract: Glioblastoma is the most common primary intracranial tumor and is also one of the most malignant central nervous system tumors. Its characteristics, such as high malignancy, abundant tumor vasculature, drug resistance, and recurrence-prone nature, cause… read more here.
Keywords: pathophysiological roles; glioma stem; stem cells; roles integrins ... See more keywords
Altered Vagal Signaling and Its Pathophysiological Roles in Functional Dyspepsia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.858612
Abstract: The vagus nerve is crucial in the bidirectional communication between the gut and the brain. It is involved in the modulation of a variety of gut and brain functions. Human studies indicate that the descending… read more here.
Keywords: roles functional; pathophysiological roles; brain; functional dyspepsia ... See more keywords
Pathophysiological Roles of Histamine Receptors in Cancer Progression: Implications and Perspectives as Potential Molecular Targets
Sign Up to like & getrecommendations! Published in 2021 at "Biomolecules"
DOI: 10.3390/biom11081232
Abstract: High levels of histamine and histamine receptors (HRs), including H1R~H4R, are found in many different types of tumor cells and cells in the tumor microenvironment, suggesting their involvement in tumor progression. This review summarizes the… read more here.
Keywords: roles histamine; pathophysiological roles; biology; histamine receptors ... See more keywords
Physiological and Pathophysiological Roles of IgM Fc Receptor (FcµR) Isoforms
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065728
Abstract: IgM is the first antibody to emerge during phylogeny, ontogeny, and immune responses and serves as a first line of defense. Effector proteins interacting with the Fc portion of IgM, such as complement and its… read more here.
Keywords: pathophysiological roles; roles igm; igm receptor; receptor isoforms ... See more keywords