Pathophysiology of Acute Kidney Injury in Critical Illness: A Narrative Review.
Sign Up to like & getrecommendations! Published in 2022 at "Comprehensive Physiology"
DOI: 10.1002/cphy.c210028
Abstract: Acute kidney injury (AKI) is a syndrome that entails a rapid decline in kidney function with or without injury. The consequences of AKI among acutely ill patients are dire and lead to higher mortality, morbidity,… read more here.
Keywords: narrative review; acute kidney; pathophysiology; kidney ... See more keywords
Preeclampsia and the Kidney: Pathophysiology and Clinical Implications.
Sign Up to like & getrecommendations! Published in 2023 at "Comprehensive Physiology"
DOI: 10.1002/cphy.c210051
Abstract: Preeclampsia and other hypertensive disorders of pregnancy are major contributors to maternal morbidity and mortality worldwide. This group of disorders includes chronic hypertension, gestational hypertension, preeclampsia, preeclampsia superimposed on chronic hypertension, and eclampsia. The body… read more here.
Keywords: clinical implications; implications preeclampsia; pathophysiology; kidney ... See more keywords
The ascending pathophysiology of cholestatic liver disease
Sign Up to like & getrecommendations! Published in 2017 at "Hepatology"
DOI: 10.1002/hep.28965
Abstract: In this review we develop the argument that cholestatic liver diseases, particularly primary biliary cholangitis and primary sclerosing cholangitis (PSC), evolve over time with anatomically an ascending course of the disease process. The first and… read more here.
Keywords: cholestatic liver; disease; liver; pathophysiology ... See more keywords
Constipation: Pathophysiology and Current Therapeutic Approaches.
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DOI: 10.1007/164_2016_111
Abstract: Chronic constipation is a common, persistent condition affecting many patients worldwide, presenting significant economic burden and resulting in substantial healthcare utilization. In addition to infrequent bowel movements, the definition of constipation includes excessive straining, a… read more here.
Keywords: primary constipation; treatment; pathophysiology; dyssynergic defecation ... See more keywords
Translational Model Systems for Complex Sodium Channel Pathophysiology in Pain.
Sign Up to like & getrecommendations! Published in 2018 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2017_91
Abstract: Chronic pain patients are often left with insufficient treatment as the pathophysiology especially of neuropathic pain remains enigmatic. Recently, genetic variations in the genes of the voltage-gated sodium channels (Navs) were linked to inherited neuropathic… read more here.
Keywords: model systems; sodium; pathophysiology; neuropathic pain ... See more keywords
Metabolomic and Proteomic Techniques for Establishing Biomarkers and Improving Our Understanding of Pathophysiology in Diabetic Nephropathy.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9841-8_18
Abstract: Molecular studies of the proteome and metabolome in readily available body fluids such as urine and blood performed in a comprehensive qualitative and quantitative way are a valuable source of information for kidney disease research.… read more here.
Keywords: analysis; disease; pathophysiology; diabetic nephropathy ... See more keywords
Iron Pathophysiology in Stroke.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-9589-5_6
Abstract: Ischemic and hemorrhagic stroke are the common types of stroke that lead to brain injury neurological deficits and mortality. All forms of stroke remain a serious health issue, and there is little successful development of… read more here.
Keywords: pathophysiology stroke; iron pathophysiology; progress; pathophysiology ... See more keywords
AICAR ameliorates high-fat diet-associated pathophysiology in mouse and ex vivo models, independent of adiponectin
Sign Up to like & getrecommendations! Published in 2017 at "Diabetologia"
DOI: 10.1007/s00125-017-4211-9
Abstract: Aims/hypothesisIn this study, we aimed to evaluate the therapeutic potential of 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), an activator of AMP-activated protein kinase, for ameliorating high-fat diet (HFD)-induced pathophysiology in mice. We also aimed to determine whether the… read more here.
Keywords: fat diet; aicar; tissue; pathophysiology ... See more keywords
Pathophysiology of Gastroesophageal Reflux Disease
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DOI: 10.1007/s00268-017-3952-4
Abstract: Gastroesophageal reflux disease pathophysiology is multifactorial and linked to a misbalance between the aggressiveness of the refluxate into the esophagus or adjacent organs and the failure of protective mechanisms associate or not to a defective… read more here.
Keywords: pathophysiology; reflux disease; gastroesophageal reflux;
Reply to “Post-surgical mutism and catatonia”
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DOI: 10.1007/s00701-017-3173-5
Abstract: Dear Editor, We thank Denysenko and Sagot for their comments on our article [1]. The authors suggest that postoperative pediatric cerebellar mutism syndrome (PPCMS) may have features of catatonia and that involvement of the dentate-thalamocerebral… read more here.
Keywords: etiology; catatonia; pathophysiology; mutism ... See more keywords
Potential Impact of Helicobacter Pylori on Hepatic Encephalopathy Pathophysiology
Sign Up to like & getrecommendations! Published in 2018 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-018-4911-0
Abstract: Wijarnpreecha et al. [1] demonstrated an association between Helicobacter pylori infection (Hp-I) and risk of hepatic encephalopathy (HE); focus only on Hp-related augmented ammonia level possibly associated with the frequent HE exacerbation, the authors concluded… read more here.
Keywords: cirrhosis; pathophysiology; hepatic encephalopathy; helicobacter pylori ... See more keywords