MicroRNAs in the pathophysiology of Alzheimer's disease and Parkinson's disease: an overview.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular neurobiology"
DOI: 10.1007/s12035-022-02727-4
Abstract: Neurodegenerative diseases are characterized by a progressive loss of neurons of the central nervous system (CNS) and serve as a major cause of morbidity, mortality and functional dependence especially among the elderly. Despite extensive research… read more here.
Keywords: pathophysiology alzheimer; disease parkinson; disease; parkinson disease ... See more keywords
α-synuclein in the pathophysiology of Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Neurodegeneration"
DOI: 10.1186/s13024-019-0320-x
Abstract: The Alzheimer’s disease (AD) afflicted brain is neuropathologically defined by extracellular amyloid-β (Aβ) plaques and intraneuronal neurofibrillary tangles composed of hyperphosphorylated tau protein. However, accumulating evidence suggests that the presynaptic protein α-synuclein (αSyn), mainly associated… read more here.
Keywords: pathophysiology alzheimer; alzheimer disease; disease; evidence ... See more keywords