Emerging role of exosomes and exosomal microRNA in cancer: pathophysiology and clinical potential
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-021-03534-5
Abstract: Exosomes are extracellular nanometric vesicles used by cells to communicate with each other. They are responsible for many pathological conditions, including tumors by transferring regulatory biomolecules that impact target cell activity. Because of their high… read more here.
Keywords: clinical potential; cancer pathophysiology; role exosomes; exosomes exosomal ... See more keywords
Coagulopathy and sepsis: Pathophysiology, clinical manifestations and treatment.
Sign Up to like & getrecommendations! Published in 2021 at "Blood reviews"
DOI: 10.1016/j.blre.2021.100864
Abstract: Sepsis is a complex syndrome with a high incidence, increasing by 8.7% annually over the last 20 years. Coagulopathy is a leading factor associated with mortality in patients with sepsis and range from slight thrombocytopenia to… read more here.
Keywords: sepsis; sepsis pathophysiology; treatment; coagulopathy sepsis ... See more keywords
Lymphedema: Pathophysiology and clinical manifestations.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2017.03.022
Abstract: Lymphedema is a localized form of tissue swelling resulting from excessive retention of lymphatic fluid in the interstitial compartment and caused by impaired lymphatic drainage. Lymphedema is classified as primary or secondary. Primary lymphedema is… read more here.
Keywords: lymphedema; dermatology; clinical manifestations; pathophysiology clinical ... See more keywords
Abdominal aortic aneurysms: pathophysiology and clinical issues
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Internal Medicine"
DOI: 10.1111/joim.13060
Abstract: AAAs are amongst the most challenging cardiovascular conditions: they are generally asymptomatic, slow progression represents the natural history and rupture is potentially life-threatening with an estimated mortality rate of 80% in patients reaching hospital and… read more here.
Keywords: medicine; aortic aneurysms; aneurysms pathophysiology; abdominal aortic ... See more keywords
Pathophysiology and clinical implications of the veno-arterial PCO2 gap
Sign Up to like & getrecommendations! Published in 2021 at "Critical Care"
DOI: 10.1186/s13054-021-03671-w
Abstract: This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2021. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2021. Further information about the Annual Update in… read more here.
Keywords: medicine; veno arterial; implications veno; clinical implications ... See more keywords
Seizures and Antiepileptic Drugs: From Pathophysiology to Clinical Practice.
Sign Up to like & getrecommendations! Published in 2017 at "Current pharmaceutical design"
DOI: 10.2174/1381612823666171115101557
Abstract: Recurrent, spontaneous seizure activity caused by abnormal neuronal firing in the brain is a hallmark of epilepsy, a common chronic neurological disorder. Recent research that has expanded the knowledge of the cellular and molecular mechanisms… read more here.
Keywords: clinical practice; drugs pathophysiology; seizures antiepileptic; antiepileptic drugs ... See more keywords
Pathophysiology and clinical management of hyperkalemia in chronic kidney disease.
Sign Up to like & getrecommendations! Published in 2023 at "Minerva medica"
DOI: 10.23736/s0026-4806.23.08465-3
Abstract: Adaptive increases in kidney and gastrointestinal excretion of K+ help to prevent hyperkalemia in patients with chronic kidney disease (CKD) as long as the glomerular filtration rate (GFR) remains >15-20 mL/min. K+ balance is maintained… read more here.
Keywords: kidney; chronic kidney; hyperkalemia; kidney disease ... See more keywords
Editorial: Toward a better understanding of the pathophysiology and clinical management of idiopathic normal pressure hydrocephalus
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.1013720
Abstract: COPYRIGHT © 2022 Karagiozov, Leinonen, Miyajima and Nakajima. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted,… read more here.
Keywords: better understanding; toward better; clinical management; understanding pathophysiology ... See more keywords
Tissue Sodium Accumulation: Pathophysiology and Clinical Implications
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11040750
Abstract: Excessive sodium intake has been well established as a risk factor for the development and progression of cardiovascular and renal diseases. Its adverse effects are achieved by renal sodium retention and related volume expansion and… read more here.
Keywords: sodium accumulation; accumulation pathophysiology; clinical implications; sodium ... See more keywords
A Systematic Review of Aminaphtone from Pathophysiology to Clinical Applications: Focus on New Rheumatological Acquisitions
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16040569
Abstract: Aminaphtone is a chemical drug that has been used for more than thirty years to treat a variety of vascular disorders, with good clinical results and a satisfying safety profile. In the last two decades,… read more here.
Keywords: aminaphtone; review; systematic review; review aminaphtone ... See more keywords