February 2023 at a glance: focus on pathophysiology and treatment
Sign Up to like & getrecommendations! Published in 2023 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.2806
Abstract: Autonomic nervous system is a main target on novel interventions.1–4 Badrov et al.5 investigated determinants of augmented muscle sympathetic nerve activity (MSNA) in 177 heart failure (HF) patients and 658 healthy volunteers. MSNA was higher… read more here.
Keywords: 2023 glance; glance focus; pathophysiology treatment; february 2023 ... See more keywords
Neurotrophic factors and neuroplasticity pathways in the pathophysiology and treatment of depression
Sign Up to like & getrecommendations! Published in 2018 at "Psychopharmacology"
DOI: 10.1007/s00213-018-4950-4
Abstract: Depression is a major health problem with a high prevalence and a heavy socioeconomic burden in western societies. It is associated with atrophy and impaired functioning of cortico-limbic regions involved in mood and emotion regulation.… read more here.
Keywords: depression; pathophysiology treatment; treatment; treatment depression ... See more keywords
Pathophysiology and treatment of cardiovascular disease in pediatric chronic kidney disease
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Nephrology"
DOI: 10.1007/s00467-017-3798-x
Abstract: Life expectancy in patients with all stages of chronic kidney disease (CKD) falls far short of that in the general population. Cardiovascular disease is the leading cause of mortality in pediatric patients with CKD. In… read more here.
Keywords: pathophysiology treatment; chronic kidney; disease; cardiovascular disease ... See more keywords
Strictures in Crohn’s Disease: From Pathophysiology to Treatment
Sign Up to like & getrecommendations! Published in 2020 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-020-06227-0
Abstract: Despite recent advances aimed to treat transmural inflammation in Crohn’s disease (CD) patients, the progression to a structuring behavior still represents an issue for clinicians. As inflammation becomes chronic and severe, the attempt to repair… read more here.
Keywords: strictures crohn; pathophysiology treatment; disease; disease pathophysiology ... See more keywords
Pathophysiology and Treatment of Canavan Disease
Sign Up to like & getrecommendations! Published in 2018 at "Neurochemical Research"
DOI: 10.1007/s11064-018-2693-6
Abstract: Canavan disease is a recessively inherited vacuolar leukodystrophy caused by ASPA mutations [1–3]. ASPA encodes aspartoacylase, an oligodendroglial enzyme required for cleavage of the abundant brain amino acid N-acetyl-l-aspartate (NAA) to acetate and l-aspartate [4].… read more here.
Keywords: treatment canavan; pathophysiology treatment; canavan; canavan disease ... See more keywords
Pathophysiology and treatment of osteoporosis: challenges for clinical practice in older people
Sign Up to like & getrecommendations! Published in 2021 at "Aging Clinical and Experimental Research"
DOI: 10.1007/s40520-021-01817-y
Abstract: Osteoporosis, a common chronic metabolic bone disease is associated with considerable morbidity and mortality. As the prevalence of osteoporosis increases with age, a paralleled elevation in the rate of incident fragility fractures will be observed.… read more here.
Keywords: older people; pathophysiology treatment; treatment osteoporosis; osteoporosis challenges ... See more keywords
Causes, pathophysiology, and treatment of pruritus in the mature patient.
Sign Up to like & getrecommendations! Published in 2018 at "Clinics in dermatology"
DOI: 10.1016/j.clindermatol.2017.10.005
Abstract: Chronic itch is a common and debilitating health condition in the elderly. There are several common causes of itch in the mature population, such as skin xerosis, immunosenescence, and neuropathic changes. In addition, skin diseases,… read more here.
Keywords: mature; causes pathophysiology; itch; pathophysiology treatment ... See more keywords
Update of pathophysiology and treatment options of seborrheic keratosis
Sign Up to like & getrecommendations! Published in 2022 at "Dermatologic Therapy"
DOI: 10.1111/dth.15934
Abstract: Seborrheic keratosis (SK) is a common, benign tumor that can occur on everybody site and can be conservatively managed. Cosmetic concerns, especially when a lesion involves the facial area, are the most common reason for… read more here.
Keywords: treatment options; pathophysiology treatment; update pathophysiology; seborrheic keratosis ... See more keywords
Cerebral Hemorrhage: Pathophysiology, Treatment, and Future Directions
Sign Up to like & getrecommendations! Published in 2022 at "Circulation Research"
DOI: 10.1161/circresaha.121.319949
Abstract: Intracerebral hemorrhage (ICH) is a devastating form of stroke with high morbidity and mortality. This review article focuses on the epidemiology, cause, mechanisms of injury, current treatment strategies, and future research directions of ICH. Incidence… read more here.
Keywords: hemorrhage; cerebral hemorrhage; pathophysiology treatment; injury ... See more keywords
A Narrative Review of the Pathophysiology and Treatment of Hypertrophic Cardiomyopathy
Sign Up to like & getrecommendations! Published in 2022 at "Southern Medical Journal"
DOI: 10.14423/smj.0000000000001478
Abstract: Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disorder that is caused by mutations in β-myosin heavy chain and myosin-binding protein C. In young athletes, HCM is the most common cause of sudden cardiac death. This… read more here.
Keywords: hypertrophic cardiomyopathy; review pathophysiology; cardiac death; hcm ... See more keywords
New Understanding on the Pathophysiology and Treatment of Constipation in Parkinson’s Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.917499
Abstract: Constipation, one of the most common prodromal non-motor symptoms of Parkinson’s disease (PD), usually occurs several years earlier than the onset of motor symptoms. Previous studies have shown that constipation occurrence increases as the disease… read more here.
Keywords: new understanding; parkinson disease; pathophysiology treatment; understanding pathophysiology ... See more keywords