NGF protects neuroblastoma cells against β‐amyloid‐induced apoptosis via the Nrf2/HO‐1 pathway
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12742
Abstract: As one of the main neurotrophic factors, nerve growth factor (NGF) participates in various processes related to viability, plasticity, and neuronal growth. NGF is known to protect against cell death and toxicity triggered by β‐amyloid… read more here.
Keywords: protects neuroblastoma; ngf protects; apoptosis; jnk jun ... See more keywords
Construction of an Alternative NAD+ De Novo Biosynthesis Pathway
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DOI: 10.1002/advs.202004632
Abstract: Abstract Nicotinamide adenine dinucleotide (NAD+) is a life essential molecule involved in versatile biological processes. To date, only two de novo biosynthetic routes to NAD+ are described, both of which start from a proteinogenic amino… read more here.
Keywords: biosynthesis; nad novo; alternative nad; c3n pathway ... See more keywords
Nature‐Inspired Tri‐Pathway Design Enabling High‐Performance Flexible Li–O2 Batteries
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Energy Materials"
DOI: 10.1002/aenm.201802964
Abstract: Trees have an abundant network of channels for the multiphase transport of water, ions, and nutrients. Recent studies have revealed that multiphase transport of ions, oxygen (O2) gas, and electrons also plays a fundamental role… read more here.
Keywords: wood; pathway design; nature inspired; performance ... See more keywords
CncC/Maf-mediated xenobiotic response pathway in insects.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.21674
Abstract: Insects have evolved resistance to almost all insecticides developed for their control. Multiple mechanisms of resistance, including enhanced metabolism and excretion of insecticides, target-site insensitivity, reduced penetration of insecticides, and avoidance behavior, have been reported.… read more here.
Keywords: insects; cncc maf; maf mediated; pathway ... See more keywords
Expanding Metabolic Capabilities Using Novel Pathway Designs: Computational Tools and Case Studies
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DOI: 10.1002/biot.201800734
Abstract: Design and selection of efficient metabolic pathways is critical for the success of metabolic engineering endeavors. Convenient pathways should not only produce the target metabolite in high yields but also are required to be thermodynamically… read more here.
Keywords: expanding metabolic; engineering; case studies; pathway ... See more keywords
Rational engineering of p‐hydroxybenzoate hydroxylase to enable efficient gallic acid synthesis via a novel artificial biosynthetic pathway
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26364
Abstract: Gallic acid (GA) is a naturally occurring phytochemical that has strong antioxidant and antibacterial activities. It is also used as a potential platform chemical for the synthesis of diverse high‐value compounds. Hydrolytic degradation of tannins… read more here.
Keywords: rational engineering; gallic acid; hydroxybenzoate hydroxylase; pathway ... See more keywords
Expression of tabersonine 16‐hydroxylase and 16‐hydroxytabersonine‐O‐methyltransferase in Catharanthus roseus hairy roots
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26487
Abstract: The monoterpene indole alkaloids vindoline and catharanthine, which are exclusively synthesized in the medicinal plant Catharanthus roseus, are the two important precursors for the production of pharmaceutically important anti‐cancer medicines vinblastine and vincristine. Hairy root… read more here.
Keywords: hairy roots; vindoline; hydroxytabersonine; pathway ... See more keywords
Nitrous oxide production in autotrophic nitrogen removal granular sludge: A modeling study
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DOI: 10.1002/bit.26937
Abstract: The sustainability of autotrophic granular system performing partial nitritation and anaerobic ammonium oxidation (anammox) for complete nitrogen removal is impaired by the production of nitrous oxide (N2O). A systematic analysis of the pathways and affecting… read more here.
Keywords: nitrogen removal; pathway; production; autotrophic nitrogen ... See more keywords
Extending the shikimate pathway for microbial production of maleate from glycerol in engineered Escherichia coli
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DOI: 10.1002/bit.27700
Abstract: Maleate is one of the most important unsaturated four‐carbon dicarboxylic acids. It serves as an attractive building block in cosmetic, polymer, and pharmaceutical industries. Currently, industrial production of maleate relies mainly on chemical synthesis using… read more here.
Keywords: engineered escherichia; production; escherichia coli; maleate ... See more keywords
Spatial organization of pathway enzymes via self‐assembly to improve 2′‐fucosyllactose biosynthesis in engineered Escherichia coli
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DOI: 10.1002/bit.28279
Abstract: As one of the most abundant components in human milk oligosaccharides, 2′‐fucosyllactose (2′‐FL) possesses versatile beneficial health effects. Although most studies focused on overexpressing or fine‐tuning the expression of pathway enzymes and achieved a striking… read more here.
Keywords: flux toward; escherichia coli; pathway enzymes; production ... See more keywords
One‐year COVID‐19 outcomes on the oncology care patient pathway: Results of a French descriptive, cross‐sectional comprehensive study (ONCOCARE‐COV)
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4817
Abstract: The COVID‐19 pandemic led to a widely documented disruption in cancer care pathway. Since a resurgence of the pandemic was expected after the first lockdown in France, the global impact on the cancer care pathway… read more here.
Keywords: oncology; pathway; covid outcomes; year covid ... See more keywords