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   Articles with "pathway" as a keyword



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NGF protects neuroblastoma cells against β‐amyloid‐induced apoptosis via the Nrf2/HO‐1 pathway

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recommendations! Published in 2019 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12742

Abstract: As one of the main neurotrophic factors, nerve growth factor (NGF) participates in various processes related to viability, plasticity, and neuronal growth. NGF is known to protect against cell death and toxicity triggered by β‐amyloid… read more here.

Keywords: protects neuroblastoma; ngf protects; apoptosis; jnk jun ... See more keywords

CDK5 interacts with MST2 and modulates the Hippo signalling pathway

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recommendations! Published in 2024 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13962

Abstract: MST2 (STK3) is a major upstream kinase in the Hippo signalling pathway, an evolutionary conserved pathway in regulation of organ size, self‐renewal and tissue homeostasis. Its downstream effectors are the transcriptional regulators YAP and TAZ.… read more here.

Keywords: hippo signalling; upstream kinase; cdk5; signalling pathway ... See more keywords

Resorcinol‐Phthalaldehyde Resins for Photosynthesis of Hydrogen Peroxide: Modulation of Electronic Structure and Integration of Dual Channel Pathway

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recommendations! Published in 2024 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202400506

Abstract: Modulating of electronic structure of photocatalyst and integration of dual channel pathway are promising strategy for efficient photosynthesis of hydrogen peroxide (H2O2) from pure water without sacrificial agent and oxygen exposure. In this work, nontoxic… read more here.

Keywords: integration dual; dual channel; resorcinol phthalaldehyde; pathway ... See more keywords
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Construction of an Alternative NAD+ De Novo Biosynthesis Pathway

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recommendations! Published in 2021 at "Advanced Science"

DOI: 10.1002/advs.202004632

Abstract: Abstract Nicotinamide adenine dinucleotide (NAD+) is a life essential molecule involved in versatile biological processes. To date, only two de novo biosynthetic routes to NAD+ are described, both of which start from a proteinogenic amino… read more here.

Keywords: biosynthesis; nad novo; alternative nad; c3n pathway ... See more keywords

Podocyte Pathogenic Bone Morphogenetic Protein‐2 Pathway and Immune Cell Behaviors in Primary Membranous Nephropathy

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recommendations! Published in 2024 at "Advanced Science"

DOI: 10.1002/advs.202404151

Abstract: Primary membranous nephropathy (PMN) is one of the leading causes of end‐stage renal disease, and the most frequent cause of massive proteinuria in nondiabetic adults, resulting in fatal complications. However, the underlying pathomechanisms of PMN… read more here.

Keywords: membranous nephropathy; podocyte pathogenic; cell; immune ... See more keywords

Procyanidin Capsules Combat ALF by Restoring Mitochondrial Homeostasis and Inhibiting Necroptosis via the PGAM5/DRP1/PINK1 Pathway.

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recommendations! Published in 2025 at "Advanced science"

DOI: 10.1002/advs.202508742

Abstract: Acute liver failure (ALF) is a life-threatening, multifactorial condition characterized by rapid progression, extensive hepatocellular necrosis, and high mortality rates. Current therapeutic options, including artificial liver support systems (ALSS) and liver transplantation, are limited by… read more here.

Keywords: pgam5 drp1; drp1 pink1; procyanidin capsules; via pgam5 ... See more keywords

Erucic Acid, Derived by Lactobacillus Crispatus, Induces Ferroptosis in Cervical Cancer Organoids Through the PPAR-δ Signaling Pathway.

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recommendations! Published in 2025 at "Advanced science"

DOI: 10.1002/advs.202512599

Abstract: The microbiome present throughout the human body serves a variety of functions. In this study, 16S rRNA sequencing is employed to uncover differences in the abundance of Lactobacillus within the vaginal microbiota between individuals with… read more here.

Keywords: cancer; cervical cancer; erucic acid; pathway ... See more keywords

Nature‐Inspired Tri‐Pathway Design Enabling High‐Performance Flexible Li–O2 Batteries

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recommendations! Published in 2019 at "Advanced Energy Materials"

DOI: 10.1002/aenm.201802964

Abstract: Trees have an abundant network of channels for the multiphase transport of water, ions, and nutrients. Recent studies have revealed that multiphase transport of ions, oxygen (O2) gas, and electrons also plays a fundamental role… read more here.

Keywords: wood; pathway design; nature inspired; performance ... See more keywords
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CncC/Maf-mediated xenobiotic response pathway in insects.

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recommendations! Published in 2020 at "Archives of insect biochemistry and physiology"

DOI: 10.1002/arch.21674

Abstract: Insects have evolved resistance to almost all insecticides developed for their control. Multiple mechanisms of resistance, including enhanced metabolism and excretion of insecticides, target-site insensitivity, reduced penetration of insecticides, and avoidance behavior, have been reported.… read more here.

Keywords: insects; cncc maf; maf mediated; pathway ... See more keywords

Expanding Metabolic Capabilities Using Novel Pathway Designs: Computational Tools and Case Studies

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recommendations! Published in 2019 at "Biotechnology Journal"

DOI: 10.1002/biot.201800734

Abstract: Design and selection of efficient metabolic pathways is critical for the success of metabolic engineering endeavors. Convenient pathways should not only produce the target metabolite in high yields but also are required to be thermodynamically… read more here.

Keywords: expanding metabolic; engineering; case studies; pathway ... See more keywords

Rational engineering of p‐hydroxybenzoate hydroxylase to enable efficient gallic acid synthesis via a novel artificial biosynthetic pathway

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recommendations! Published in 2017 at "Biotechnology and Bioengineering"

DOI: 10.1002/bit.26364

Abstract: Gallic acid (GA) is a naturally occurring phytochemical that has strong antioxidant and antibacterial activities. It is also used as a potential platform chemical for the synthesis of diverse high‐value compounds. Hydrolytic degradation of tannins… read more here.

Keywords: rational engineering; gallic acid; hydroxybenzoate hydroxylase; pathway ... See more keywords