Application of serine integrases for secondary metabolite pathway assembly in Streptomyces
Sign Up to like & getrecommendations! Published in 2020 at "Synthetic and Systems Biotechnology"
DOI: 10.1016/j.synbio.2020.05.006
Abstract: Serine integrases have been shown to be efficient tools for metabolic pathway assembly. To further improve the flexibility and efficiency of pathway engineering via serine integrases, we explored how multiple orthogonally active serine integrases can… read more here.
Keywords: serine; pathway assembly; application serine; serine integrases ... See more keywords
Reconstitution of the lipid-linked oligosaccharide pathway for assembly of high-mannose N-glycans
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-09752-3
Abstract: The asparagine (N)-linked Man9GlcNAc2 is required for glycoprotein folding and secretion. Understanding how its structure contributes to these functions has been stymied by our inability to produce this glycan as a homogenous structure of sufficient… read more here.
Keywords: reconstitution lipid; pathway assembly; linked oligosaccharide; oligosaccharide pathway ... See more keywords