Human drug-pathway association prediction based on network consistency projection
Sign Up to like & getrecommendations! Published in 2022 at "Computational biology and chemistry"
DOI: 10.1016/j.compbiolchem.2022.107624
Abstract: We present a novel computational method for drug-pathway association prediction based on known drug-pathway associations. The association between a drug and a pathway needs to be examined to not only explain the cause and enable… read more here.
Keywords: drug; drug pathway; pathway association; network ... See more keywords
Probabilistic prioritization of candidate pathway association with pathway score
Sign Up to like & getrecommendations! Published in 2018 at "BMC Bioinformatics"
DOI: 10.1186/s12859-018-2411-z
Abstract: BackgroundCurrent methods for gene-set or pathway analysis are usually designed to test the enrichment of a single gene-set. Once the analysis is carried out for each of the sets under study, a list of significant… read more here.
Keywords: pathway score; association; pathway association; pathway ... See more keywords
PAST: The Pathway Association Studies Tool to Infer Biological Meaning from GWAS Datasets
Sign Up to like & getrecommendations! Published in 2020 at "Plants"
DOI: 10.3390/plants9010058
Abstract: In recent years, a bioinformatics method for interpreting genome-wide association study (GWAS) data using metabolic pathway analysis has been developed and successfully used to find significant pathways and mechanisms explaining phenotypic traits of interest in… read more here.
Keywords: gwas datasets; past pathway; association; pathway association ... See more keywords