Proteins of the Lectin Pathway of complement activation at the site of injury in subarachnoid hemorrhage compared with peripheral blood
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DOI: 10.1002/brb3.1728
Abstract: A subarachnoid hemorrhage (SAH) is a debilitating stroke. Activation of the lectin pathway (LP) of the complement system in SAH patients could worsen the prognosis; however, conflicting results have been reported. This potentially reflects that… read more here.
Keywords: site injury; pathway complement; lectin pathway; subarachnoid hemorrhage ... See more keywords
Genetic variability shapes the alternative pathway complement activity and predisposition to complement‐related diseases
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DOI: 10.1111/imr.13131
Abstract: The implementation of next‐generation sequencing technologies has provided a sharp picture of the genetic variability in the components and regulators of the alternative pathway (AP) of the complement system and has revealed the association of… read more here.
Keywords: genetic variability; pathway complement; alternative pathway; complement ... See more keywords
Local Activation of the Alternative Pathway of Complement System in Mycotic Keratitis Patient Tear
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DOI: 10.3389/fcimb.2020.00205
Abstract: Aspergillus flavus and Fusarium solani are the predominant causative agents of mycotic keratitis in the tropical part of the world. Tear proteins play a major role in the innate immune response against these fungal infections… read more here.
Keywords: pathway complement; complement; mycotic keratitis; patient tear ... See more keywords
Functional and Structural Characterization of a Potent C1q Inhibitor Targeting the Classical Pathway of the Complement System
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DOI: 10.3389/fimmu.2020.01504
Abstract: The classical pathway of complement is important for protection against pathogens and in maintaining tissue homeostasis, but excessive or aberrant activation is directly linked to numerous pathologies. We describe the development and in vitro characterization… read more here.
Keywords: classical pathway; inhibitor; pathway complement; c1q ... See more keywords
Dengue and the Lectin Pathway of the Complement System
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DOI: 10.3390/v13071219
Abstract: Dengue is a mosquito-borne viral disease causing significant health and economic burdens globally. The dengue virus (DENV) comprises four serotypes (DENV1-4). Usually, the primary infection is asymptomatic or causes mild dengue fever (DF), while secondary… read more here.
Keywords: dengue lectin; pathway complement; lectin pathway; complement system ... See more keywords