Differential regulation of Hippo signaling pathway components between 8‐cell and blastocyst stages of bovine preimplantation embryogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23564
Abstract: The Hippo signaling pathway is an important regulator of lineage segregation (trophectoderm and inner cell mass) during blastocyst formation in the mouse embryos. However, the role and regulation of Hippo signaling pathway components during bovine… read more here.
Keywords: pathway components; regulation hippo; signaling pathway; cell blastocyst ... See more keywords
RdDM pathway components differentially modulate Tobamovirus symptom development
Sign Up to like & getrecommendations! Published in 2020 at "Plant Molecular Biology"
DOI: 10.1007/s11103-020-01051-6
Abstract: The crop yield losses induced by phytoviruses are mainly associated with the symptoms of the disease. DNA modifications as methylation can modulate the information coded by the sequence, process named epigenetics. Viral infection can change… read more here.
Keywords: plant; production symptoms; components differentially; role ... See more keywords
Emerging ways to treat breast cancer: will promises be met?
Sign Up to like & getrecommendations! Published in 2018 at "Cellular Oncology"
DOI: 10.1007/s13402-018-0409-1
Abstract: BackgroundBreast cancer (BC) is the most common cancer among women and it is responsible for more than 40,000 deaths in the United States and more than 500,000 deaths worldwide each year. In previous decades, the… read more here.
Keywords: ways treat; emerging ways; breast cancer; treat breast ... See more keywords
Molecular characterization of mitochondrial Zucchini and its relation to nuage-piRNA pathway components in Bombyx mori ovary-derived BmN4 cells.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.09.107
Abstract: Piwi-interacting RNAs (piRNAs) are a class of small non-coding RNAs that associate with PIWI subfamily proteins, which play an important role in transposon silencing in animal germ cell. The piRNAs biogenesis is divided into two… read more here.
Keywords: derived bmn4; pirna pathway; nuage; ovary derived ... See more keywords
Regulation of Hippo pathway components by FSH in testis.
Sign Up to like & getrecommendations! Published in 2019 at "Reproductive biology"
DOI: 10.1016/j.repbio.2019.01.003
Abstract: The transition of testicular Sertoli cells (Sc) from a proliferative state during infancy to a non proliferative functionally mature state at the onset of puberty is essential for proper spermatogenic progression. The Hippo signaling pathway… read more here.
Keywords: regulation hippo; pubertal; hippo pathway; fsh ... See more keywords
Meta-analysis suggests evidence of novel stress-related pathway components in Orsay virus - Caenorhabditis elegans viral model
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-40762-9
Abstract: The genetic model organism, Caenorhabditis elegans (C. elegans), shares many genes with humans and is the best-annotated of the eukaryotic genome. Therefore, the identification of new genes and pathways is unlikely. Nevertheless, host-pathogen interaction studies… read more here.
Keywords: analysis; caenorhabditis elegans; pathway components; orsay virus ... See more keywords
FGFR1-Activated Translation of WNT Pathway Components with Structured 5' UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer research"
DOI: 10.1158/0008-5472.can-18-0631
Abstract: Cooperativity between WNT and FGF signaling is well documented in embryonic development and cancer progression, but the molecular mechanisms underlying this cross-talk remain elusive. In this study, we interrogated the dynamics of RNA levels, ribosome… read more here.
Keywords: wnt; fgf signaling; translation; pathway components ... See more keywords
Abstract 5712: Potential clinical significance of downregulation of MAPK pathway components mRNA expression in head and neck squamous cell carcinoma (HNSCC)
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-5712
Abstract: We previously showed the MAPK pathway can be mutationally activated, and may implicate drug sensitivity in HNSCC [1]. Here, we report that RNA expression of several MAPK pathway components may be associated with HNSCC patients9… read more here.
Keywords: mapk pathway; hnscc; expression; cell ... See more keywords
SENP8 limits aberrant neddylation of NEDD8 pathway components to promote cullin-RING ubiquitin ligase function
Sign Up to like & getrecommendations! Published in 2017 at "eLife"
DOI: 10.7554/elife.24325
Abstract: NEDD8 is a ubiquitin-like modifier most well-studied for its role in activating the largest family of ubiquitin E3 ligases, the cullin-RING ligases (CRLs). While many non-cullin neddylation substrates have been proposed over the years, validation… read more here.
Keywords: neddylation; cullin ring; pathway components; aberrant neddylation ... See more keywords