Articles with "pathway drug" as a keyword



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LKB1/AMPK Pathway and Drug Response in Cancer: A Therapeutic Perspective

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Published in 2019 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2019/8730816

Abstract: Inactivating mutations of the tumor suppressor gene Liver Kinase B1 (LKB1) are frequently detected in non-small-cell lung cancer (NSCLC) and cervical carcinoma. Moreover, LKB1 expression is epigenetically regulated in several tumor types. LKB1 has an… read more here.

Keywords: lkb1 ampk; response; lkb1; cancer ... See more keywords