De Novo Pathway Enrichment with KeyPathwayMiner
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9873-9_14
Abstract: Biomolecular networks such as protein-protein interaction networks provide a static picture of the interplay of genes and their products, and, consequently, they fail to capture dynamic changes taking place during the development of complex diseases.… read more here.
Keywords: keypathwayminer; biology; pathway enrichment; enrichment keypathwayminer ... See more keywords
On the influence of several factors on pathway enrichment analysis
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbac143
Abstract: Abstract Pathway enrichment analysis has become a widely used knowledge-based approach for the interpretation of biomedical data. Its popularity has led to an explosion of both enrichment methods and pathway databases. While the elegance of… read more here.
Keywords: enrichment analysis; pathway enrichment; analysis; influence several ... See more keywords
Comprehensive investigation of pathway enrichment methods for functional interpretation of LC-MS global metabolomics data
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac553
Abstract: BACKGROUND Global or untargeted metabolomics is widely used to comprehensively investigate metabolic profiles under various pathophysiological conditions such as inflammations, infections, responses to exposures or interactions with microbial communities. However, biological interpretation of global metabolomics… read more here.
Keywords: enrichment methods; metabolomics data; pathway enrichment; functional interpretation ... See more keywords
Nine quick tips for pathway enrichment analysis
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1010348
Abstract: Pathway enrichment analysis (PEA) is a computational biology method that identifies biological functions that are overrepresented in a group of genes more than would be expected by chance and ranks these functions by relevance. The… read more here.
Keywords: quick tips; enrichment analysis; nine quick; pathway enrichment ... See more keywords
An integrative analysis of an lncRNA–mRNA competing endogenous RNA network to identify functional lncRNAs in uterine leiomyomas with RNA sequencing
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1053845
Abstract: Objective: To explore the functions of mRNAs and lncRNAs in the occurrence of uterine leiomyomas (ULs) and further clarify the pathogenesis of UL by detecting the differential expression of mRNAs and lncRNAs in 10 cases… read more here.
Keywords: network; rna sequencing; rna; pathway enrichment ... See more keywords