Structures of the mannose-6-phosphate pathway enzyme, GlcNAc-1-phosphotransferase
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DOI: 10.1073/pnas.2203518119
Abstract: Significance Lysosomes are cellular organelles containing a variety of degradative enzymes. The protein N-acetylglucosamine-1-phosphotransferase (GNPT) is responsible for directing these enzymes to be delivered to lysosomes. Genetic mutations in GNPT cause the diseases mucolipidosis types… read more here.
Keywords: phosphate pathway; enzyme glcnac; mannose phosphate; structures mannose ... See more keywords