Marked functional recovery and imaging response of refractory optic pathway glioma to BRAFV600E inhibitor therapy: a report of two cases
Sign Up to like & getrecommendations! Published in 2018 at "Child's Nervous System"
DOI: 10.1007/s00381-018-3739-4
Abstract: BackgroundDespite appropriate therapeutic interventions, progressive optic pathway glioma (OPG) in children may result in loss of vision and other neurologic morbidities. Molecularly targeted therapy against the MAP kinase pathway holds promise in improving outcomes while… read more here.
Keywords: inhibitor; response; pathway glioma; pathway ... See more keywords
Endocrine Long-Term Follow-Up of Children with Neurofibromatosis Type 1 and Optic Pathway Glioma
Sign Up to like & getrecommendations! Published in 2017 at "Hormone Research in Paediatrics"
DOI: 10.1159/000458525
Abstract: Background/Aims: Children with optic pathway glioma (OPG) face sequelae related to tumour location and treatment modalities. We aimed to assess the prevalence of hypothalamic-pituitary dysfunctions in children with neurofibromatosis type 1 (NF1) and OPG who… read more here.
Keywords: pathway glioma; tumour location; children neurofibromatosis; neurofibromatosis type ... See more keywords
A new era for optic pathway glioma: A developmental brain tumor with life-long health consequences
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2023.1038937
Abstract: Optic pathway and hypothalamic glioma (OPHG) are low-grade brain tumors that arise from any part of the visual pathways frequently involving the hypothalamus. The tumors grow slowly and present with features driven by their precise… read more here.
Keywords: health; optic pathway; brain; life ... See more keywords
Neurosurgery for Optic Pathway Glioma: Optimizing Multidisciplinary Management
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Surgery"
DOI: 10.3389/fsurg.2022.884250
Abstract: Optic pathway glioma (OPG) comprises 10% of pediatric brain tumors and 40% of all pediatric low-grade gliomas (pLGGs). While generally considered benign pathologically, many require interventions with chemotherapy, radiation, or targeted therapies. Management has historically… read more here.
Keywords: neurosurgery optic; management; optic pathway; pathway glioma ... See more keywords