Targeting a novel apoptotic pathway in human disease
Sign Up to like & getrecommendations! Published in 2023 at "BioEssays"
DOI: 10.1002/bies.202200231
Abstract: Apoptotic pathways have always been regarded as a key‐player in preserving tissue and organ homeostasis. Excessive activation or resistance to activation of cell death signaling may indeed be responsible for several mechanisms of disease, including… read more here.
Keywords: targeting novel; apoptotic pathway; disease; death ... See more keywords
Cigarette smoke condensate affects the retinoid pathway in human amnion.
Sign Up to like & getrecommendations! Published in 2017 at "Placenta"
DOI: 10.1016/j.placenta.2017.08.076
Abstract: INTRODUCTION The preterm premature rupture of membranes (PPROM) is a frequent pathology responsible of more than 30% of preterm births. Tobacco smoking is one of the most frequently described risk factors identified and contributes to… read more here.
Keywords: cigarette smoke; retinoid pathway; amnion; human amnion ... See more keywords
A distinct assembly pathway of the human 39S late pre-mitoribosome
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DOI: 10.1038/s41467-021-24818-x
Abstract: Assembly of the mitoribosome is largely enigmatic and involves numerous assembly factors. Little is known about their function and the architectural transitions of the pre-ribosomal intermediates. Here, we solve cryo-EM structures of the human 39S… read more here.
Keywords: 39s late; distinct assembly; pre; assembly pathway ... See more keywords
Activation of the TREM‐1 pathway in human monocytes by periodontal pathogens and oral commensal bacteria
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DOI: 10.1111/omi.12169
Abstract: Periodontitis is a highly prevalent disease caused in part by an aberrant host response to the oral multi-species biofilm. A balance between the oral bacteria and host immunity is essential for oral health. Imbalances in… read more here.
Keywords: human monocytes; trem pathway; trem; pathway human ... See more keywords
Intensive Statin Therapy Compromises the Adiponectin-AdipoR Pathway in the Human Monocyte-Macrophage Lineage.
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DOI: 10.1161/strokeaha.119.026280
Abstract: Background and Purpose- Statins are widely used for cardiovascular disease prevention through cholesterol-lowering and anti-inflammatory effects. Adiponectin, an anti-inflammatory adipokine, acts via two receptors, AdipoR1 and AdipoR2, to exert atheroprotective effects on the vasculature. We… read more here.
Keywords: macrophage; expression; adipor pathway; adiponectin adipor ... See more keywords