Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-α
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-12207-4
Abstract: To facilitate proper mitotic cell partitioning, the Golgi disassembles by suppressing vesicle fusion. However, the underlying mechanism has not been characterized previously. Here, we report a Ran pathway-independent attenuation mechanism that allows Importin-α (a nuclear… read more here.
Keywords: golgi disassembly; gm130; golgi; ran pathway ... See more keywords
Developing a pathway-independent and full-autonomous global resource allocation strategy to dynamically switching phenotypic states
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-19432-2
Abstract: A grand challenge of biological chemical production is the competition between synthetic circuits and host genes for limited cellular resources. Quorum sensing (QS)-based dynamic pathway regulations provide a pathway-independent way to rebalance metabolic flux over… read more here.
Keywords: phenotypic states; resource allocation; allocation strategy; strategy ... See more keywords
A pathway independent multi-modular ordered control system based on thermosensors and CRISPRi improves bioproduction in Bacillus subtilis
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac476
Abstract: Abstract Dynamic regulation is an effective strategy for control of gene expression in microbial cell factories. In some pathway contexts, several metabolic modules must be controlled in a time dependent or ordered manner to maximize… read more here.
Keywords: bacillus subtilis; control; modular ordered; ordered control ... See more keywords
Manganese Mediates Its Antiviral Functions in a cGAS-STING Pathway Independent Manner
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15030646
Abstract: The innate immune system is the first line of host defense sensing viral infection. Manganese (Mn) has recently been found to be involved in the activation of the innate immune DNA-sensing cGAS-STING pathway and subsequent… read more here.
Keywords: manner; sting pathway; cgas sting; mn2 ... See more keywords