The S100A10 Pathway Mediates an Occult Hyperfibrinolytic Subtype in Trauma Patients.
Sign Up to like & getrecommendations! Published in 2019 at "Annals of surgery"
DOI: 10.1097/sla.0000000000002733
Abstract: OBJECTIVE To determine the characteristics of trauma patients with low levels of fibrinolysis as detected by viscoelastic hemostatic assay (VHA) and explore the underlying mechanisms of this subtype. BACKGROUND Hyperfibrinolysis is a central component of… read more here.
Keywords: low levels; patients low; pathway mediates; trauma patients ... See more keywords
The Hippo pathway mediates Semaphorin signaling
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abl9806
Abstract: Semaphorins were originally identified as axonal guidance molecules, but they also control processes such as vascular development and tumorigenesis. The downstream signaling cascades of Semaphorins in these biological processes remain unclear. Here, we show that… read more here.
Keywords: hippo pathway; mediates semaphorin; semaphorin signaling; pathway mediates ... See more keywords
The Toll pathway mediates Drosophila resilience to Aspergillus mycotoxins through specific Bomanins
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DOI: 10.15252/embr.202256036
Abstract: Host defense against infections encompasses resistance, which targets microorganisms for neutralization or elimination, and resilience/disease tolerance, which allows the host to withstand/tolerate pathogens and repair damages. In Drosophila, the Toll signaling pathway is thought to… read more here.
Keywords: resilience; aspergillus mycotoxins; toll pathway; pathway mediates ... See more keywords
Activation of Hippo signaling pathway mediates mitochondria dysfunction and dilated cardiomyopathy in mice
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DOI: 10.7150/thno.62302
Abstract: Rationale: Mitochondrial dysfunction facilitates heart failure development forming a therapeutic target, but the mechanism involved remains unclear. We studied whether the Hippo signaling pathway mediates mitochondrial abnormalities that results in onset of dilated cardiomyopathy (DCM).… read more here.
Keywords: signaling pathway; hippo signaling; dysfunction; pathway mediates ... See more keywords