Antidepressant effect of repeated ketamine administration on kynurenine pathway metabolites in patients with unipolar and bipolar depression
Sign Up to like & getrecommendations! Published in 2018 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2018.09.007
Abstract: Ketamine has rapid antidepressant effects on treatment-resistant depression, but the biological mechanism underpinning this effect is less clear. Our aims were to examine whether kynurenine pathway metabolites were altered by six infusions of ketamine and… read more here.
Keywords: depression; pathway metabolites; effect; patients unipolar ... See more keywords
Changes in Kynurenine Pathway Metabolites After Acute Psychosocial Stress in Healthy Males: A Single-Arm Pilot Study.
Sign Up to like & getrecommendations! Published in 2021 at "Stress"
DOI: 10.1080/10253890.2021.1959546
Abstract: Chronic stress is associated with an increased conversion of tryptophan (TRP) into kynurenine (KYN). However, only a few studies investigated KYN pathway metabolite concentrations following acute stress in healthy subjects. We hypothesized that TRP/KYN metabolism… read more here.
Keywords: stress induction; pathway metabolites; trp; kyn pathway ... See more keywords
Optimization of extraction conditions for LC-ToF-MS analysis of mevalonate pathway metabolites in engineered E. coli strain via statistical experimental designs.
Sign Up to like & getrecommendations! Published in 2022 at "Talanta"
DOI: 10.2139/ssrn.4129022
Abstract: Isoprenoids give rise to many functional products used today such as flavours, fragrances and even pharmaceutical compounds. Mevalonate pathway metabolites are the key intermediates that affect the production yield of isoprenoids. With increasing demand and… read more here.
Keywords: metabolites engineered; pathway metabolites; statistical experimental; mevalonate pathway ... See more keywords