Pathway Refactoring for Efficient 7-Dehydrocholesterol Production in Saccharomyces cerevisiae.
Sign Up to like & getrecommendations! Published in 2025 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.5c00032
Abstract: 7-Dehydrocholesterol (7-DHC) is a subcutaneous sterol and a precursor to various active vitamin D3. Here, a Saccharomyces cerevisiae strain equipped with the de novo biosynthetic pathway for 7-DHC was constructed. 109.0 mg L-1 of 7-DHC… read more here.
Keywords: pathway refactoring; saccharomyces cerevisiae; dhc; dehydrocholesterol ... See more keywords