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   Articles with "pathway related" as a keyword



Co‐mutation landscape and clinical significance of RAS pathway related gene mutations in patients with myelodysplastic syndrome

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recommendations! Published in 2022 at "Hematological Oncology"

DOI: 10.1002/hon.3099

Abstract: Single gene mutations in the RAS pathway are uncommon and of unknown significance in myelodysplastic syndrome (MDS) patients, RAS pathway‐related gene mutations (RASwaymut) as a whole may be significant and require further elucidation. The clinical… read more here.

Keywords: gene mutations; ras pathway; pathway related; mds patients ... See more keywords
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Estrogen pathway related genes and their association with risk of postpartum psychosis: A case control study.

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recommendations! Published in 2017 at "Asian journal of psychiatry"

DOI: 10.1016/j.ajp.2017.01.014

Abstract: • METTL13 gene rs2232825 locus or a linked functional locus may modulate the vulnerability to development of postpartum psychosis. read more here.

Keywords: estrogen pathway; postpartum psychosis; postpartum; related genes ... See more keywords

Genetic variants in mTOR-pathway-related genes contribute to osteoarthritis susceptibility.

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recommendations! Published in 2019 at "International immunopharmacology"

DOI: 10.1016/j.intimp.2019.105960

Abstract: The mTOR signaling pathway has been demonstrated to be related to the development of osteoarthritis (OA) by regulating expression of autophagy regulators. Few studies have shed light on the association of mTOR-pathway-related gene variants with… read more here.

Keywords: mtor pathway; risk; irs1 rs1801278; mtor ... See more keywords

Uncovering Hippo pathway-related biomarkers in acute myocardial infarction via scRNA-seq binding transcriptomics

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-94820-6

Abstract: This study investigated Hippo signaling pathway-related biomarkers in acute myocardial infarction (AMI). First, differentially expressed genes (DEGs) between AMI patients and controls were identified. Consensus clustering then classified AMI subtypes, followed by subtype-specific DEG screening.… read more here.

Keywords: pathway related; biomarkers acute; myocardial infarction; acute myocardial ... See more keywords

The cGAS-STING pathway-related gene signature can predict patient prognosis and immunotherapy responses in prostate adenocarcinoma

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recommendations! Published in 2022 at "Medicine"

DOI: 10.1097/md.0000000000031290

Abstract: The cyclic GMP-AMP synthase-stimulator of the interferon genes (cGAS-STING) pathway is essential in inflammation-driven tumor occurrence and progression. However, the prognostic roles and immune functions of cGAS-STING pathway-related genes in patients with prostate adenocarcinoma (PRAD)… read more here.

Keywords: prognosis; sting pathway; pathway related; risk ... See more keywords

Urinary insulin signaling pathway related proteins may serve as potential biomarkers for monitoring diabetes mellitus without hypertension and hyperlipidemia

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recommendations! Published in 2023 at "Medicine"

DOI: 10.1097/md.0000000000032862

Abstract: The insulin signaling pathway plays an important role in the development of diabetes mellitus. The expression of insulin signaling pathway related proteins in the urine of diabetic patients has not been reported. The aim of… read more here.

Keywords: signaling pathway; hypertension; pathway related; insulin signaling ... See more keywords

Variations of Wnt/β‐catenin pathway‐related genes in susceptibility to knee osteoarthritis: A three‐centre case‐control study

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recommendations! Published in 2019 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.14696

Abstract: Excessive activation of the Wnt signalling pathway in the articular cartilage is demonstrated to be related to the onset and severity of osteoarthritis (OA). However, few studies have investigated the association between variants in Wnt‐pathway‐related… read more here.

Keywords: decreased risk; risk; variations wnt; related genes ... See more keywords

Variations within Toll‐like receptor (TLR) and TLR signaling pathway‐related genes and their synergistic effects on the risk of Guillain‐Barré syndrome

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recommendations! Published in 2022 at "Journal of the Peripheral Nervous System"

DOI: 10.1111/jns.12484

Abstract: Guillain‐Barré syndrome (GBS) is the commonest post‐infectious polyradiculopathy. Although genetic background of the host seems to play an important role in the susceptibility to GBS, genes conferring major risk are not yet known. Dysregulation of… read more here.

Keywords: pathway related; variations within; risk; tlr ... See more keywords

Expression of PAPP-A2 and IGF Pathway-Related Proteins in the Hip Joint of Normal Rat and Those with Developmental Dysplasia of the Hip

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recommendations! Published in 2019 at "International Journal of Endocrinology"

DOI: 10.1155/2019/7691531

Abstract: Developmental dysplasia of the hip (DDH) is one of the major causes of child disability and early osteoarthritis. Genetic factors play an important role, but which still remain unclear. Pregnancy-associated plasma protein-A2 (PAPP-A2), a special… read more here.

Keywords: expression papp; hip; related proteins; pathway related ... See more keywords

Signature and Molecular Mechanism of Mitochondrial Energy Metabolism Pathway-Related Genes in Lung Adenocarcinoma

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recommendations! Published in 2022 at "Disease Markers"

DOI: 10.1155/2022/3201600

Abstract: Objective The mitochondrial energy metabolic pathway (MEMP) is the primary energy metabolism of tumor cells, and its disruption may promote cancer emergence, spreading, and immune escape. However, there is a lack of studies to determine… read more here.

Keywords: related genes; pathway related; risk group; energy ... See more keywords

Machine Learning Identifies Pan-Cancer Landscape of Nrf2 Oxidative Stress Response Pathway-Related Genes

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recommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/8450087

Abstract: Background Oxidative stress produced a large amount of reactive oxygen species (ROS), which played a pivotal role in balanced ability and determining cell fate. The activated Nrf2 signaling pathway that responds to the excessive ROS… read more here.

Keywords: cancer; related genes; pathway related; signaling pathway ... See more keywords