Inhibition of the NAD salvage pathway in schistosomes impairs metabolism, reproduction, and parasite survival
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DOI: 10.1371/journal.ppat.1008539
Abstract: NAD, a key co-enzyme required for cell metabolism, is synthesized via two pathways in most organisms. Since schistosomes apparently lack enzymes required for de novo NAD biosynthesis, we evaluated whether these parasites, which infect >200… read more here.
Keywords: metabolism; salvage pathway; pathway schistosomes; inhibition nad ... See more keywords