An anterograde pathway for sensory axon degeneration gated by a cytoplasmic action of the transcriptional regulator P53.
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DOI: 10.1016/j.devcel.2021.03.011
Abstract: Axon remodeling through sprouting and pruning contributes to the refinement of developing neural circuits. A prominent example is the pruning of developing sensory axons deprived of neurotrophic support, which is mediated by a caspase-dependent (apoptotic)… read more here.
Keywords: pathway sensory; p53 anterograde; sensory axons; p53 ... See more keywords