Modulating the wnt signaling pathway with small molecules
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DOI: 10.1002/pro.3122
Abstract: Wnt signaling is a critical component during embryonic development and also plays an important role in regulating adult tissue homeostasis. Abnormal activation of Wnt signaling has been implicated in many cancers, while reduced activity of… read more here.
Keywords: pathway small; wnt signaling; wnt; modulating wnt ... See more keywords
Signaling Pathway and Small-Molecule Drug Discovery of FGFR: A Comprehensive Review
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2022.860985
Abstract: Targeted therapy is a groundbreaking innovation for cancer treatment. Among the receptor tyrosine kinases, the fibroblast growth factor receptors (FGFRs) garnered substantial attention as promising therapeutic targets due to their fundamental biological functions and frequently… read more here.
Keywords: small molecule; fgfr; signaling pathway; review ... See more keywords