Directly to the Point: Dopamine Persistently Enhances Excitability of Direct Pathway Striatal Neurons
Sign Up to like & getrecommendations! Published in 2020 at "Neuron"
DOI: 10.1016/j.neuron.2020.04.005
Abstract: In this issue of Neuron, Lahiri and Bevan (2020) investigate the effects of dopamine release on striatal projection neurons. Using perforated patch recordings and optogenetics, they show that dopamine release persistently enhances the intrinsic excitability… read more here.
Keywords: striatal neurons; pathway striatal; direct pathway; excitability direct ... See more keywords
Chemogenetic inhibition of direct pathway striatal neurons normalizes pathological, cue‐induced reinstatement of drug‐seeking in rats
Sign Up to like & getrecommendations! Published in 2019 at "Addiction Biology"
DOI: 10.1111/adb.12594
Abstract: Addiction to drugs such as cocaine is marked by cycles of compulsive drug‐taking and drug‐seeking behavior. Although the transition to addiction is thought to recruit neural processes in dorsal striatum, little is known regarding the… read more here.
Keywords: addiction; drug seeking; pathway striatal; drug ... See more keywords