Suicidality and Activation of the Kynurenine Pathway of Tryptophan Metabolism.
Sign Up to like & getrecommendations! Published in 2017 at "Current topics in behavioral neurosciences"
DOI: 10.1007/7854_2016_5
Abstract: A recent report by the World Health Organization declared suicide to be a major global problem. With more than 800,000 lives lost each year, suicide is calculated to be the 14th leading cause of death… read more here.
Keywords: pathway tryptophan; tryptophan metabolism; pathway; kynurenine pathway ... See more keywords
Kynurenine Pathway of Tryptophan Metabolism in Patients with Familial Mediterranean Fever.
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DOI: 10.1093/mr/roac016
Abstract: BACKGROUND Familial Mediterranean fever (FMF) is an autoinflammatory syndrome characterized by recurrent episodes of fever and aseptic polyserositis. Subclinical inflammation generates a hidden threat to the development of FMF complications such as amyloidosis in attack-free… read more here.
Keywords: kynurenine pathway; familial mediterranean; rheumatology; pathway tryptophan ... See more keywords
Role of the indoleamine-2,3-dioxygenase/kynurenine pathway of tryptophan metabolism in behavioral alterations in a hepatic encephalopathy rat model
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-017-1037-9
Abstract: BackgroundThis study aims to explore the role of indoleamine-2,3-dioxygenase (IDO)/kynurenine (KYN) pathway of tryptophan (TRY) metabolism in behavioral alterations observed in hepatic encephalopathy (HE) rats.MethodsExpression levels of proinflammatory cytokines were tested by QT-PCR and ELISA,… read more here.
Keywords: role indoleamine; metabolism; pathway tryptophan; metabolism behavioral ... See more keywords