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Published in 2019 at "Trends in molecular medicine"
DOI: 10.1016/j.molmed.2019.05.006
Abstract: Despite the identification of several dozens of common genetic variants associated with Alzheimer's disease (AD) and Parkinson's disease (PD), most of the genetic risk remains uncharacterised. Therefore, it is important to understand the role of…
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Keywords:
pathways alzheimer;
parkinson;
identify shared;
shared pathways ... See more keywords
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Published in 2022 at "Drug Research"
DOI: 10.1055/a-2008-7948
Abstract: Abstract Neurofibrillary tangles and plaques containing tau serve as the biological markers for Alzheimer disease (AD) and pathogenesis is widely believed to be driven by the production and deposition of the β-amyloid peptide (Aβ). The…
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Keywords:
disease;
alzheimer disease;
rage pathways;
amyloid peptide ... See more keywords
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Published in 2018 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.14256
Abstract: Alzheimer's disease (AD) belongs to one of the most multifactorial, complex and heterogeneous morbidity‐leading disorders. Despite the extensive research in the field, AD pathogenesis is still at some extend obscure. Mechanisms linking AD with certain…
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Keywords:
disease specific;
pathways alzheimer;
alzheimer disease;
pathological pathways ... See more keywords
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2
Published in 2018 at "Brain Sciences"
DOI: 10.3390/brainsci8020027
Abstract: The ATP-binding cassette (ABC) reporter family functions to regulate the homeostasis of phospholipids and cholesterol in the central nervous system, as well as peripheral tissues. ABCA7 belongs to the A subfamily of ABC transporters, which…
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Keywords:
pathways alzheimer;
alzheimer disease;
pathogenic pathways;
disease ... See more keywords