Mathematical modeling of multiple pathways in colorectal carcinogenesis using dynamical systems with Kronecker structure
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1008970
Abstract: Like many other types of cancer, colorectal cancer (CRC) develops through multiple pathways of carcinogenesis. This is also true for colorectal carcinogenesis in Lynch syndrome (LS), the most common inherited CRC syndrome. However, a comprehensive… read more here.
Keywords: multiple pathways; kronecker structure; colorectal carcinogenesis; pathways colorectal ... See more keywords
THERAPEUTIC TARGETING OF MOLECULAR PATHWAYS IN COLORECTAL CANCER.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental oncology"
DOI: 10.32471/exp-oncology.2312-8852.vol-44-no-1.17455
Abstract: Mutations in tumor suppressor genes, cell signaling, and genes associated with DNA repair lead to onset of colorectal cancer (CRC). Even though most CRC patients get clinical benefits from conventional treatments such as chemotherapy and… read more here.
Keywords: therapeutic targeting; colorectal cancer; molecular pathways; pathways colorectal ... See more keywords