Pathways controlling neurotoxicity and proteostasis in mitochondrial complex I deficiency
Sign Up to like & getrecommendations! Published in 2024 at "Human Molecular Genetics"
DOI: 10.1093/hmg/ddae018
Abstract: Neuromuscular disorders caused by dysfunction of the mitochondrial respiratory chain are common, severe and untreatable. We recovered a number of mitochondrial genes, including electron transport chain components, in a large forward genetic screen for mutations… read more here.
Keywords: pathways controlling; controlling neurotoxicity; proteostasis; complex deficiency ... See more keywords
Molecular Pathways Controlling Autophagy in Pancreatic Cancer
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2017.00028
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is one of the few cancer types where the 5-year survival rate shows no improvement. Despite conflicting evidence, the majority of data points to an essential role for autophagy in PDAC… read more here.
Keywords: pdac; controlling autophagy; pathways controlling; cancer ... See more keywords