A systematically derived overview of the non-ubiquitous pathways and genes that define the molecular and genetic signature of the healthy trabecular meshwork.
Sign Up to like & getrecommendations! Published in 2022 at "Genomics"
DOI: 10.1016/j.ygeno.2022.110280
Abstract: PURPOSE The trabecular meshwork (TM) is situated in the most frontal part of the eye and is thought to play an important role in the regulation of the eye pressure. However, this tissue is rather… read more here.
Keywords: trabecular meshwork; non ubiquitous; ubiquitous pathways; signature ... See more keywords
Global, pathway and gene coverage of three Illumina arrays with respect to inflammatory and immune-related pathways
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Human Genetics"
DOI: 10.1038/s41431-019-0441-2
Abstract: Genome-wide association studies have led in the past to the discovery of susceptibility genes for many diseases including cancer and inflammatory conditions. However, a number of these studies did not realise their full potential. A… read more here.
Keywords: gene coverage; array; global coverage; coverage ... See more keywords
Identification of key pathways and genes in the progression of silicosis based on WGCNA
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DOI: 10.1080/08958378.2022.2102700
Abstract: Abstract Silicosis, induced by inhaling silica particles in workplaces, is one of the most common occupational diseases. The prognosis of silicosis and its consequent fibrosis is extremely poor due to limited treatment modalities and lack… read more here.
Keywords: identification key; silicosis; pathways genes; silicosis fibrosis ... See more keywords
A multi-omics approach for identifying important pathways and genes in human cancer
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DOI: 10.1186/s12859-018-2476-8
Abstract: BackgroundCancer develops when pathways controlling cell survival, cell fate or genome maintenance are disrupted by the somatic alteration of key driver genes. Understanding how pathway disruption is driven by somatic alterations is thus essential for… read more here.
Keywords: human cancer; analysis; pathway; cancer ... See more keywords
Key Pathways and Genes of Arabidopsis thaliana and Arabidopsis halleri Roots under Cadmium Stress Responses: Differences and Similarities
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DOI: 10.3390/plants12091793
Abstract: Cadmium (Cd) is among the world’s major health concerns, as it renders soils unsuitable and unsafe for food and feed production. Phytoremediation has the potential to remediate Cd-polluted soils, but efforts are still needed to… read more here.
Keywords: stress; halleri; cadmium; differences similarities ... See more keywords
Transcriptome sequencing identifies key pathways and genes involved in gastric adenocarcinoma
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DOI: 10.3892/mmr.2018.9370
Abstract: The present study aimed to investigate the key pathways and genes associated with gastric adenocarcinoma via transcriptome sequencing. Five pairs of gastric adenocarcinoma tissue and normal tumor-adjacent tissue were harvested. After sequencing, raw data were… read more here.
Keywords: key pathways; gastric adenocarcinoma; transcriptome sequencing; genes cluster ... See more keywords
Identification of key pathways and genes in nasopharyngeal carcinoma using bioinformatics analysis.
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DOI: 10.3892/ol.2019.10133
Abstract: Nasopharyngeal carcinoma (NPC) is one of the most common malignancies in the head and neck. The aim of the current study was to identify the key pathways and genes involved in NPC through bioinformatics analysis… read more here.
Keywords: pathways genes; bioinformatics analysis; key pathways; degs ... See more keywords