Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.04.031
Abstract: SUMMARY PD-L1 and PD-L2 are ligands for the PD-1 immune inhibiting checkpoint that can be induced in tumors by interferon exposure, leading to immune evasion. This process is important for immunotherapy based on PD-1 blockade.… read more here.
Keywords: signaling pathways; pathways regulating; interferon; expression ... See more keywords
Metabolic pathways regulating colorectal cancer: a potential therapeutic approach.
Sign Up to like & getrecommendations! Published in 2022 at "Current pharmaceutical design"
DOI: 10.2174/1381612828666220922111342
Abstract: Colorectal cancer (CRC) is one of the most prevalent cancers globally. Despite recent progress in identifying etiologies and molecular genetics as well as new therapeutic approaches, the clinical outcome of current CRC therapies remains poor.… read more here.
Keywords: regulating colorectal; pathways regulating; crc; colorectal cancer ... See more keywords
Integrative analysis revealed the role of glucagon-like peptide-2 in improving experimental colitis in mice by inhibiting inflammatory pathways, regulating glucose metabolism, and modulating gut microbiota
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1174308
Abstract: Introduction Ulcerative colitis (UC) is an inflammatory bowel disease characterized by recurrent and remitting inflammation of the mucosa of the colon and rectum, the incidence of which is on the rise. Glucagon-like peptide-2 (GLP-2) is… read more here.
Keywords: gut microbiota; inflammatory pathways; pathways regulating; glucagon like ... See more keywords