MET Signaling Pathways, Resistance Mechanisms, and Opportunities for Target Therapies
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DOI: 10.3390/ijms232213898
Abstract: The MET gene, known as MET proto-oncogene receptor tyrosine kinase, was first identified to induce tumor cell migration, invasion, and proliferation/survival through canonical RAS-CDC42-PAK-Rho kinase, RAS-MAPK, PI3K-AKT-mTOR, and β-catenin signaling pathways, and its driver mutations,… read more here.
Keywords: target therapies; met signaling; resistance; pathways resistance ... See more keywords