Shared signaling pathways and targeted therapy by natural bioactive compounds for obesity and type 2 diabetes.
Sign Up to like & getrecommendations! Published in 2022 at "Critical reviews in food science and nutrition"
DOI: 10.1080/10408398.2022.2148090
Abstract: Epidemiological evidence showed that patients suffering from obesity and T2DM are significantly at higher risk for chronic low-grade inflammation, oxidative stress, nonalcoholic fatty liver (NAFLD) and intestinal flora imbalance. Increasing evidence of pathological characteristics illustrates… read more here.
Keywords: bioactive compounds; pathways targeted; shared signaling; obesity ... See more keywords
Cell survival pathways targeted in rare lung disease affecting women
Sign Up to like & getrecommendations! Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.adi1215
Abstract: Novel drug targets are identified in lymphangioleiomyomatosis (LAM), a rare disease in women. These targets focus on uterine transcription factors necessary for LAM cell survival. read more here.
Keywords: rare lung; disease; targeted rare; pathways targeted ... See more keywords
Immunosuppressive Signaling Pathways as Targeted Cancer Therapies
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DOI: 10.3390/biomedicines10030682
Abstract: Immune response has been shown to play an important role in defining patient prognosis and response to cancer treatment. Tumor-induced immunosuppression encouraged the recent development of new chemotherapeutic agents that assists in the augmentation of… read more here.
Keywords: cancer; signaling pathways; cancer cells; immunosuppressive signaling ... See more keywords