The Comparison of Newly Diagnosed Invasive Breast Patient Cohorts in Genomics Evidence Neoplasia Information Exchange Biopharma Collaborative (GENIE‐BPC) and Other Real‐World Databases
Sign Up to like & getrecommendations! Published in 2024 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.5851
Abstract: Oncology databases that integrate genomic and clinical data have become valuable resources for precision medicine. However, the generalizability of these databases has not been comprehensively assessed. read more here.
Keywords: newly diagnosed; invasive breast; patient cohorts; comparison newly ... See more keywords
Strength of patient cohorts and biobanks for cardiomyopathy research
Sign Up to like & getrecommendations! Published in 2020 at "Netherlands Heart Journal"
DOI: 10.1007/s12471-020-01456-4
Abstract: In 2011 the Netherlands Heart Foundation allocated funding (CVON, Cardiovasculair Onderzoek Nederland) to stimulate collaboration between clinical and preclinical researchers on specific areas of research. One of those areas involves genetic heart diseases, which are… read more here.
Keywords: cohorts biobanks; research; cardiomyopathy research; strength patient ... See more keywords
Identification of cancer chemotherapy regimens and patient cohorts in administrative claims: challenges, opportunities, and a proposed algorithm.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of medical economics"
DOI: 10.1080/13696998.2023.2187196
Abstract: BACKGROUND Real-world evidence is a valuable source of information in healthcare. This study describes the challenges and successes during algorithm development to identify cancer cohorts and multi-agent chemotherapy regimens from claims data to perform a… read more here.
Keywords: patients cancer; csf; chemotherapy regimens; patient cohorts ... See more keywords
A serotonin transporter polymorphism is associated with postoperative nausea and vomiting: An observational study in two different patient cohorts.
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Anaesthesiology"
DOI: 10.1097/eja.0000000000001014
Abstract: BACKGROUND Clinical risk factors for postoperative nausea and vomiting (PONV) are well described, whereas genetic findings are conflicting. OBJECTIVE The aim of this study was to investigate a possible association of genetic variants and nongenetic… read more here.
Keywords: postoperative nausea; nausea vomiting; patient cohorts; study ... See more keywords
Dynamic longitudinal patient cohorts using hospital electronic medical record (EMR) data via secure data environment (SDE) technology to generate real-world evidence (RWE).
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.16_suppl.e23320
Abstract: e23320 Background: Patient cohorts using clinically rich Real-World Data (RWD) extracted from medical records have been used to generate RWE. These patient cohorts are static, containing only data until the time of data extraction; typically,… read more here.
Keywords: oncology; generate; patient cohorts; sde technology ... See more keywords
Cohort Builder: A Software Pipeline for Generating Patient Cohorts with Predetermined Baseline Characteristics from Medical Records and Raw Ophthalmic Imaging Data
Sign Up to like & getrecommendations! Published in 2024 at "Studies in health technology and informatics"
DOI: 10.3233/shti240613
Abstract: In clinical research, the analysis of patient cohorts is a widely employed method for investigating relevant healthcare questions. The ability to automatically extract large-scale patient cohorts from hospital systems is vital in order to unlock… read more here.
Keywords: imaging data; cohort builder; medical records; software pipeline ... See more keywords
Musculoskeletal spine modeling in large patient cohorts: how morphological individualization affects lumbar load estimation
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2024.1363081
Abstract: Introduction: Achieving an adequate level of detail is a crucial part of any modeling process. Thus, oversimplification of complex systems can lead to overestimation, underestimation, and general bias of effects, while elaborate models run the… read more here.
Keywords: musculoskeletal spine; modeling large; large patient; patient cohorts ... See more keywords
Generating Realistic Synthetic Patient Cohorts: Enforcing Statistical Distributions, Correlations, and Logical Constraints
Sign Up to like & getrecommendations! Published in 2025 at "Algorithms"
DOI: 10.3390/a18080475
Abstract: Large, high-quality patient datasets are essential for applications like economic modeling and patient simulation. However, real-world data is often inaccessible or incomplete. Synthetic patient data offers an alternative, and current methods often fail to preserve… read more here.
Keywords: correlations logical; real world; synthetic patient; patient cohorts ... See more keywords
Effectiveness of the Use of Standardized Vocabularies on Epilepsy Patient Cohort Generation
Sign Up to like & getrecommendations! Published in 2022 at "Healthcare Informatics Research"
DOI: 10.4258/hir.2022.28.3.240
Abstract: Objectives This study investigated the effectiveness of using standardized vocabularies to generate epilepsy patient cohorts with local medical codes, SNOMED Clinical Terms (SNOMED CT), and International Classification of Diseases tenth revision (ICD-10)/Korean Classification of Diseases-7… read more here.
Keywords: icd kcd; patient cohorts; snomed icd; cohort ... See more keywords