Diabetes in the older patient: heterogeneity requires individualisation of therapeutic strategies
Sign Up to like & getrecommendations! Published in 2018 at "Diabetologia"
DOI: 10.1007/s00125-018-4547-9
Abstract: Owing to the worldwide increase in life expectancy, the high incidence of diabetes in older individuals and the improved survival of people with diabetes, about one-third of all individuals with diabetes are now older than… read more here.
Keywords: patient heterogeneity; diabetes older; heterogeneity requires; older individuals ... See more keywords
Methods and measures to quantify ICU patient heterogeneity
Sign Up to like & getrecommendations! Published in 2021 at "Journal of biomedical informatics"
DOI: 10.1016/j.jbi.2021.103768
Abstract: Patients in intensive care units are heterogeneous and the daily prediction of their days to discharge (DTD) a complex task that practitioners and computers are not always able to solve satisfactorily. In order to make… read more here.
Keywords: icu patient; heterogeneity; patient heterogeneity; measures quantify ... See more keywords
Intra-patient Heterogeneity of BRAF and NRAS Molecular Alterations in Primary Melanoma and Metastases.
Sign Up to like & getrecommendations! Published in 2019 at "Acta dermato-venereologica"
DOI: 10.2340/00015555-3382
Abstract: Mutations in MAPK signalling genes are driver events in melanoma, and have therapeutic relevance in the metastatic and adjuvant setting. This study evaluated the intra-patient heterogeneity of BRAF, NRAS and c-KIT mutational status between 30… read more here.
Keywords: braf nras; patient heterogeneity; heterogeneity braf; intra patient ... See more keywords
Case Study: Intra-Patient Heterogeneity of Aneurysmal Tissue Properties
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2018.00082
Abstract: Introduction: Current recommendations for surgical treatment of abdominal aortic aneurysms (AAAs) rely on the assessment of aortic diameter as a marker for risk of rupture. The use of aortic size alone may overlook the role… read more here.
Keywords: heterogeneity aneurysmal; heterogeneity; patient heterogeneity; tissue ... See more keywords
Proof-of-Concept Pilot Study on Comprehensive Spatiotemporal Intra-Patient Heterogeneity for Colorectal Cancer With Liver Metastasis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.855463
Abstract: Introduction The mechanisms underlying high drug resistance and relapse rates after multi-modal treatment in patients with colorectal cancer (CRC) and liver metastasis (LM) remain poorly understood. Objective We evaluate the potential translational implications of intra-patient… read more here.
Keywords: liver metastasis; heterogeneity; patient heterogeneity; oncology ... See more keywords
High-Throughput Profiling of Colorectal Cancer Liver Metastases Reveals Intra- and Inter-Patient Heterogeneity in the EGFR and WNT Pathways Associated with Clinical Outcome
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14092084
Abstract: Simple Summary Tumor heterogeneity can greatly influence therapy outcome and patient survival. In this study, we aimed at unraveling inter- and intra-patient heterogeneity of colorectal cancer liver metastases (CRLM). To this end, we comprehensively characterized… read more here.
Keywords: heterogeneity; outcome; colorectal cancer; liver metastases ... See more keywords