Modeling Down Syndrome with Patient iPSCs Reveals Cellular and Migration Deficits of GABAergic Neurons
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DOI: 10.1016/j.stemcr.2018.02.001
Abstract: Summary The brain of Down syndrome (DS) patients exhibits fewer interneurons in the cerebral cortex, but its underlying mechanism remains unknown. By morphometric analysis of cortical interneurons generated from DS and euploid induced pluripotent stem… read more here.
Keywords: gabaergic neurons; syndrome patient; ipscs reveals; migration ... See more keywords