A nanoplasmonic label-free surface-enhanced Raman scattering strategy for non-invasive cancer genetic subtyping in patient samples.
Sign Up to like & getrecommendations! Published in 2017 at "Nanoscale"
DOI: 10.1039/c6nr09928a
Abstract: Simple nucleic acid detection methods could facilitate the progress of disease diagnostics for clinical uses. An attractive strategy is label-free surface-enhanced Raman scattering (SERS) due to its capability of providing structural fingerprinting of analytes that… read more here.
Keywords: free surface; patient samples; cancer; label free ... See more keywords
Updates on the study of lysosomal protein dynamics: possibilities for the clinic
Sign Up to like & getrecommendations! Published in 2023 at "Expert Review of Proteomics"
DOI: 10.1080/14789450.2023.2190515
Abstract: ABSTRACT Introduction The lysosome is the main degradative organelle of almost all mammalian cells, fulfilling important functions in macromolecule recycling, metabolism, and signaling. Lysosomal dysfunction is connected to a continuously growing number of pathologic conditions,… read more here.
Keywords: lysosomal protein; study lysosomal; protein dynamics; patient samples ... See more keywords
Abstract 44: CG′806, a first-in-class FLT3/BTK inhibitor, exhibits potent activity against AML patient samples with mutant or wild type FLT3, as well as other hematologic malignancy subtypes
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Cancer Research"
DOI: 10.1158/1557-3265.hemmal17-44
Abstract: The Fms-like receptor tyrosine kinase 3 (FLT3) is expressed in approximately 90% of acute myeloid leukemia (AML), almost all B-lineage acute lymphoblastic leukemia (B-ALL), and some other hematologic malignancy subtype patients. Approximately one third of… read more here.
Keywords: inhibitor; flt3; patient samples; hematologic malignancy ... See more keywords
Comprehensive molecular profiling of paired patient samples of primary and metastatic (met) pancreatic ductal adenocarcinoma (PDAC).
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.4114
Abstract: 4114Background: Pancreatic cancer is the third leading cause of cancer-related death in the U.S. The vast majority of pancreatic cancer is PDAC (90%). Most patients with PDAC die from complications... read more here.
Keywords: comprehensive molecular; pdac; paired patient; molecular profiling ... See more keywords
The impact of SARS-CoV-2 measures on patient samples and complication rates in spine surgery – A single center analysis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Surgery"
DOI: 10.3389/fsurg.2022.1086960
Abstract: Objective Over the past two years during the pandemic, the German health system has taken drastic measures, like the continuous use of face masks for all staff, restrictions of hospital visits as well as cancellation… read more here.
Keywords: complication rates; surgery; complication; impact ... See more keywords
Metagenomic Antimicrobial Susceptibility Testing from Simulated Native Patient Samples
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DOI: 10.3390/antibiotics12020366
Abstract: Genomic antimicrobial susceptibility testing (AST) has been shown to be accurate for many pathogens and antimicrobials. However, these methods have not been systematically evaluated for clinical metagenomic data. We investigate the performance of in-silico AST… read more here.
Keywords: simulated native; susceptibility testing; patient samples; native patient ... See more keywords