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Published in 2020 at "International journal of medical informatics"
DOI: 10.1016/j.ijmedinf.2019.104073
Abstract: OBJECTIVE To simulate the clinical reasoning of doctors, retrieve analogous patients of an index patient automatically and predict diagnoses by the similar/dissimilar patients. METHODS We proposed a novel patient-similarity-based framework for diagnostic prediction, which is…
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Keywords:
analogy;
similarity based;
similarity;
patient similarity ... See more keywords
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Published in 2018 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2018.05.037
Abstract: Clinical research and practice in the 21st century is poised to be transformed by analysis of computable electronic medical records and population-level genome-scale patient profiles. Genomic data capture genetic and environmental state, providing information on…
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Keywords:
medicine;
patient similarity;
precision medicine;
similarity networks ... See more keywords
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Published in 2020 at "Journal of the American Medical Informatics Association : JAMIA"
DOI: 10.1093/jamia/ocaa159
Abstract: Abstract Defining patient-to-patient similarity is essential for the development of precision medicine in clinical care and research. Conceptually, the identification of similar patient cohorts appears straightforward; however, universally accepted definitions remain elusive. Simultaneously, an explosion…
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Keywords:
workshop;
similarity;
medical informatics;
patient similarity ... See more keywords
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Published in 2020 at "F1000Research"
DOI: 10.12688/f1000research.26429.1
Abstract: Patient classification based on clinical and genomic data will further the goal of precision medicine. Interpretability is of particular relevance for models based on genomic data, where sample sizes are relatively small (in the hundreds),…
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Keywords:
similarity;
netdx software;
patient similarity;
patient classifiers ... See more keywords
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Published in 2020 at "F1000Research"
DOI: 10.12688/f1000research.26429.2
Abstract: Patient classification based on clinical and genomic data will further the goal of precision medicine. Interpretability is of particular relevance for models based on genomic data, where sample sizes are relatively small (in the hundreds),…
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Keywords:
similarity;
netdx software;
patient similarity;
patient classifiers ... See more keywords
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Published in 2019 at "Studies in health technology and informatics"
DOI: 10.3233/shti190496
Abstract: A comprehensive scheme of patient similarity based on different types of patient features and the corresponding similarity measurements was proposed. Patient similarity was used in building a predictive model where training samples similar to the…
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Keywords:
measurement based;
similarity measurement;
study patient;
similarity ... See more keywords
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Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.786710
Abstract: A timely diagnosis is a key challenge for many rare diseases. As an expanding group of rare and severe monogenic disorders with a broad spectrum of clinical manifestations, ciliopathies, notably renal ciliopathies, suffer from important…
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Keywords:
patient similarity;
similarity;
diagnosis;
patient ... See more keywords