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   Articles with "patient variability" as a keyword



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Addressing patient to patient variability for autologous CAR T therapies.

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recommendations! Published in 2020 at "Journal of pharmaceutical sciences"

DOI: 10.1016/j.xphs.2020.12.015

Abstract: Chimeric Antigen Receptor (CAR) T cell therapy clinical trials have had unprecedented success in the endeavors to cure cancer patients, particularly those having hematological cancers. As researchers learn more about the ways to make CAR… read more here.

Keywords: addressing patient; patient variability; car cells; cancer patients ... See more keywords
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Tacrolimus Intra-Patient Variability, Time in Therapeutic Range, and Risk of De Novo Donor-Specific Antibodies.

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recommendations! Published in 2019 at "Transplantation"

DOI: 10.1097/tp.0000000000002913

Abstract: BACKGROUND Tacrolimus (TAC) is the most important agent for maintenance immunosuppression and prevention of immunologic injury to the renal allograft, yet there remains no consensus on how best to monitor drug therapy. Both high TAC… read more here.

Keywords: patient variability; risk; variability; tac ... See more keywords
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Intra‐patient variability in tacrolimus exposure in pediatric liver transplant recipients: Evolution, risk factors, and impact on patient outcomes

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recommendations! Published in 2019 at "Pediatric Transplantation"

DOI: 10.1111/petr.13388

Abstract: This study aims to investigate the evolution and factors associated with TAC IPV and its impact on patient outcomes in pediatric LT recipients. read more here.

Keywords: evolution; impact patient; patient outcomes; variability tacrolimus ... See more keywords
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Spontaneous variability of pre-dialysis concentrations of uremic toxins over time in stable hemodialysis patients

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recommendations! Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0186010

Abstract: Background and aim Numerous outcome studies and interventional trials in hemodialysis (HD) patients are based on uremic toxin concentrations determined at one single or a limited number of time points. The reliability of these studies… read more here.

Keywords: uremic toxins; time; variability; concentrations uremic ... See more keywords

Combined impact of the inter and intra-patient variability of tacrolimus blood level on allograft outcomes in kidney transplantation

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recommendations! Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.1037566

Abstract: Introduction Tacrolimus (TAC) has been widely used as an immunosuppressant after kidney transplantation (KT); however, the combined effects of intra-patient variability (IPV) and inter-patient variability of TAC-trough level (C0) in blood remain controversial. This study… read more here.

Keywords: allograft outcomes; high ipv; inter; ipv ... See more keywords