Effectiveness and safety of apixaban therapy in daily-care patients with atrial fibrillation: results from the Dresden NOAC Registry
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-017-1519-8
Abstract: The effectiveness and safety of apixaban for stroke prevention in atrial fibrillation (SPAF) demonstrated in ARISTOTLE needs to be confirmed in daily care. To evaluate effectiveness and safety of apixaban therapy in SPAF patients in… read more here.
Keywords: 100 patient; patient years; safety apixaban; daily care ... See more keywords
Safety and Tolerability of Empagliflozin in Patients with Type 2 Diabetes: Pooled Analysis of Phase I–III Clinical Trials
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DOI: 10.1007/s12325-017-0573-0
Abstract: IntroductionWe characterized the safety and tolerability of empagliflozin in patients with type 2 diabetes (T2DM) randomized 1:1:1 to placebo, empagliflozin 10 mg, or empagliflozin 25 mg in clinical trials.MethodsPooled data were analyzed from patients with T2DM treated… read more here.
Keywords: 100 patient; empagliflozin patients; safety tolerability; empagliflozin ... See more keywords
Bleeding and ischaemic events after first bleed in anticoagulated atrial fibrillation patients: risk and timing.
Sign Up to like & getrecommendations! Published in 2022 at "European heart journal"
DOI: 10.1093/eurheartj/ehac587
Abstract: AIMS To determine the risk of subsequent adverse clinical outcomes in anticoagulated patients with atrial fibrillation (AF) who experienced a new bleeding event. METHODS AND RESULTS Anticoagulated AF patients were followed in two prospective cohort… read more here.
Keywords: major bleeding; per 100; patient years; 100 patient ... See more keywords
Safety of the JAK and TNF inhibitors in rheumatoid arthritis: real world data from the Hong Kong Biologics Registry.
Sign Up to like & getrecommendations! Published in 2023 at "Rheumatology"
DOI: 10.1093/rheumatology/kead198
Abstract: OBJECTIVES To compare the incidence of major adverse cardiovascular events (MACEs), cancer and infective complications in rheumatoid arthritis (RA) patients using the JAK (JAKis) and TNF inhibitors (TNFis). METHOD A retrospective analysis of data from… read more here.
Keywords: hong kong; tnf inhibitors; rheumatoid arthritis; patient years ... See more keywords
The Safety of Soft Contact Lenses in Children
Sign Up to like & getrecommendations! Published in 2017 at "Optometry and Vision Science"
DOI: 10.1097/opx.0000000000001078
Abstract: ABSTRACT Purpose There is increasing interest in fitting children with soft contact lenses. This review collates data from a range of studies to estimate the incidence of complications, specifically corneal infiltrative events and microbial keratitis,… read more here.
Keywords: soft contact; contact lenses; patient years; year olds ... See more keywords
Direct oral anticoagulant use in patients with antiphospholipid syndrome and unprovoked venous thromboembolism: a single centre experience
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Haematology"
DOI: 10.1111/bjh.17634
Abstract: The recommendations on the use of long-term anticoagulation in antiphospholipid syndrome (APS) changed following two randomised-control trials (RCT) by Pengo et al. and Ordi-Ros et al. They showed that patients with APS had higher rates… read more here.
Keywords: doac; recurrence; per 100; triple positive ... See more keywords
SAT0276 Uveitis during anti-tnf therapy in patients with axial spondyloarthritis: a paradoxical event or disease manifestation?
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.4071
Abstract: Background Although widely recognised as extra-articular manifestations of axial spondyloarthritis (axSpA), uveitis developing throughout anti-TNFα treatment is difficult to be classified as disease related or paradoxical event. Objectives We aimed to evaluate the incidence of… read more here.
Keywords: tnf; anti tnf; paradoxical event; uveitis ... See more keywords
Age-based (
Sign Up to like & getrecommendations! Published in 2020 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2020-218992
Abstract: A randomised, open-label, blinded endpoint post-authorisation safety study (Study A3921133; NCT02092467; database not locked and subject to change) evaluated the safety of tofacitinib 5 mg and 10 mg twice daily (BID) versus tumour necrosis factor inhibitors… read more here.
Keywords: age; age based; based years; tofacitinib bid ... See more keywords
Safety of ixekizumab in patients with psoriatic arthritis: data from four clinical trials with over 2000 patient-years of exposure
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2021-222027
Abstract: Objectives Ixekizumab, a high-affinity monoclonal antibody that selectively targets interleukin 17A (IL-17A), has shown significant efficacy in the treatment of psoriatic arthritis (PsA) and sustained long-term clinical response without unexpected new safety outcome for an… read more here.
Keywords: safety; psoriatic arthritis; patient years; four clinical ... See more keywords
Stroke Risk and Antithrombotic Treatment During Follow-up of Patients With Ischemic Stroke and Cortical Superficial Siderosis
Sign Up to like & getrecommendations! Published in 2022 at "Neurology"
DOI: 10.1212/wnl.0000000000201723
Abstract: Background and Objectives In patients with ischemic stroke (IS) or transient ischemic attack (TIA) and cortical superficial siderosis (cSS), there are few data regarding the risk of future cerebrovascular events and also about the benefits… read more here.
Keywords: css; 000 patient; patient years; risk ... See more keywords