Serum levels of glial fibrillary acidic protein in patients with amyotrophic lateral sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51708
Abstract: To compare serum levels of the astrocyte biomarker glial fibrillary acidic protein (GFAP) in patients with amyotrophic lateral sclerosis (ALS) and neurologically healthy controls and to analyze the relations between serum GFAP (sGFAP) and phenotype… read more here.
Keywords: patients amyotrophic; fibrillary acidic; serum levels; acidic protein ... See more keywords
Genotype–phenotype association of TARDBP mutations in Chinese patients with amyotrophic lateral sclerosis: a single-center study and systematic review of published literature
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neurology"
DOI: 10.1007/s00415-022-11042-w
Abstract: This study aims to determine the genetic and clinical features of TARDBP-mutated patients in our cohort of Chinese patients with amyotrophic lateral sclerosis (ALS) combined with data in the literature. We performed TARDBP mutation screening… read more here.
Keywords: review; patients amyotrophic; chinese patients; tardbp ... See more keywords
Serum troponin T in patients with amyotrophic lateral sclerosis
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neurologica Belgica"
DOI: 10.1007/s13760-017-0855-y
Abstract: also underwent cardiac troponin I (cTnI) measurement. Known causes of cTnT elevation were excluded by means of 12-lead ECG (performed at the same time of cTnT sampling), clinical history, clinical evaluation (hemodynamic stability), laboratory findings,… read more here.
Keywords: troponin patients; amyotrophic lateral; troponin; serum troponin ... See more keywords
Plasma from some patients with amyotrophic lateral sclerosis exhibits elevated formaldehyde levels
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2019.116589
Abstract: INTRODUCTION The aim of this study was to determine whether patients with amyotrophic lateral sclerosis (ALS) exhibit higher plasma levels of formaldehyde (FA) than controls, and to look for alterations in levels of FA precursors.… read more here.
Keywords: plasma; lateral sclerosis; amyotrophic lateral; plasma levels ... See more keywords
Temporal muscle thickness and survival in patients with amyotrophic lateral sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Neurological Research"
DOI: 10.1080/01616412.2022.2096004
Abstract: ABSTRACT Temporal muscle thickness (TMT) is a new potential MRI biomarker, which has shown prognostic relevance in neuro-oncology. We aim at investigating the potential prognostic value of TMT in patients with Amyotrophic Lateral Sclerosis (ALS).… read more here.
Keywords: patients amyotrophic; muscle thickness; lateral sclerosis; temporal muscle ... See more keywords
Phosphorylated TDP-43 aggregates in peripheral motor nerves of patients with amyotrophic lateral sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Brain"
DOI: 10.1093/brain/awab285
Abstract: Abstract Phosphorylated TDP-43 (pTDP-43) aggregates in the cytoplasm of motor neurons and neuroglia in the brain are one of the pathological hallmarks of amyotrophic lateral sclerosis. Although the axons exceed the total volume of motor… read more here.
Keywords: lateral sclerosis; patients amyotrophic; ptdp; motor ... See more keywords
Upper motor neuron dysfunction is associated with the presence of behavioural impairment in patients with amyotrophic lateral sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Neurology"
DOI: 10.1111/ene.15243
Abstract: Increasing evidence shows that approximately half of patients with amyotrophic lateral sclerosis (ALS) display cognitive (ALSci) or behavioural (ALSbi) impairment, or both (ALScbi). The aim of our study was to assess whether the burden of… read more here.
Keywords: behavioural impairment; patients amyotrophic; lateral sclerosis; motor neuron ... See more keywords
Lower hypothalamic volume with lower body mass index is associated with shorter survival in patients with amyotrophic lateral sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Neurology"
DOI: 10.1111/ene.15589
Abstract: Weight loss in patients with amyotrophic lateral sclerosis (ALS) is associated with faster disease progression and shorter survival. Decreased hypothalamic volume is proposed to contribute to weight loss due to loss of appetite and/or hypermetabolism.… read more here.
Keywords: patients amyotrophic; survival; hypothalamic volume; volume ... See more keywords
Factors Affecting Energy Metabolism and Prognosis in Patients with Amyotrophic Lateral Sclerosis
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DOI: 10.1159/000518908
Abstract: Background/Aims: Nutritional status is a factor affecting prognosis in patients with amyotrophic lateral sclerosis (ALS). Here, we aimed to clarify the factors associated with hypermetabolism and the prognosticators of ALS. Methods: Forty-two inpatients (22 men,… read more here.
Keywords: energy; metabolism; prognosis; amyotrophic lateral ... See more keywords
Serial ultrasound assessment of diaphragmatic function and clinical outcome in patients with amyotrophic lateral sclerosis
Sign Up to like & getrecommendations! Published in 2019 at "BMC Pulmonary Medicine"
DOI: 10.1186/s12890-019-0924-5
Abstract: BackgroundDiaphragmatic assessment by ultrasound (US) is a non-invasive and useful method in the clinical management of patients with Amyotrophic Lateral Sclerosis (ALS). The aim of our observational study was to evaluate the impact of serial… read more here.
Keywords: function; amyotrophic lateral; assessment; diaphragmatic function ... See more keywords
Increased Risk of Venous Thromboembolism in Patients With Amyotrophic Lateral Sclerosis
Sign Up to like & getrecommendations! Published in 2023 at "Neurology: Clinical Practice"
DOI: 10.1212/cpj.0000000000200110
Abstract: Background and Objectives Reduced mobility in patients with amyotrophic lateral sclerosis (ALS) is hypothesized to increase the risk of venous thromboembolism (VTE). A few small, single-center studies have investigated the risk of VTE in patients… read more here.
Keywords: patients amyotrophic; patients als; vte; risk ... See more keywords