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Published in 2021 at "Cancer Cytopathology"
DOI: 10.1002/cncy.22519
Abstract: The recently published 2021 guidelines for the management of patients with anaplastic thyroid cancer from the American Thyroid Association provide updated recommendations and guidance for the treatment of this rare but lethal thyroid cancer and…
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Keywords:
patients anaplastic;
american thyroid;
anaplastic thyroid;
ata ... See more keywords
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Published in 2021 at "Clinical Pharmacokinetics"
DOI: 10.1007/s40262-021-01015-z
Abstract: Lorlatinib demonstrated efficacy (including intracranial activity) in patients with anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC) in a phase I/II study (NCT01970865). This analysis describes the pharmacokinetics (PK) of lorlatinib following single and…
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Keywords:
phase;
single multiple;
alk positive;
multiple dosing ... See more keywords
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Published in 2017 at "Clinical radiology"
DOI: 10.1016/j.crad.2016.11.013
Abstract: AIM To investigate the prognostic role of subventricular zone (SVZ) involvement in anaplastic glioma. MATERIALS AND METHODS The magnetic resonance imaging and clinical data of 160 patients with histopathologically confirmed anaplastic glioma treated at Beijing…
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Keywords:
anaplastic glioma;
svz involvement;
patients anaplastic;
glioma ... See more keywords
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Published in 2019 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noz175.904
Abstract: Anaplastic oligodendrogliomas are a type of high grade glioma defined molecularly by the 1p19q co-deletion. Currently, there is no curative therapy, and some studies have estimated median survival is estimated to be approximately 5 years.…
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Keywords:
chemotherapy;
anaplastic oligodendroglioma;
analysis;
patients anaplastic ... See more keywords
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Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.e20516
Abstract: e20516Background: Crizotinib is an oral small-molecule tyrosine kinase inhibitor targeting ALK, MET, and ROS1 tyrosine kinases. It was first approved by the Food and Drug Administration (FDA) in 20...
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Keywords:
efficacy safety;
kinase;
anaplastic lymphoma;
safety crizotinib ... See more keywords
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Published in 2017 at "Haematologica"
DOI: 10.3324/haematol.2017.177972
Abstract: Patients with anaplastic lymphoma kinase-positive anaplastic large cell lymphoma often present with B-symptoms or hemophagocytosis and generate an anti-tumor immune response. Specific serum cytokine levels or profiles may reflect the tumor burden, non-specific immune stimulation…
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Keywords:
large cell;
patients anaplastic;
cell;
anaplastic large ... See more keywords