An update: current and prospective treatments for adult-onset Still’s disease
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Orphan Drugs"
DOI: 10.1080/21678707.2017.1311252
Abstract: ABSTRACT Introduction: Adult-onset Still’s disease (AOSD) is an uncommon systemic inflammatory disease characterized by a spiking fever, an evanescent skin rash, polyarthralgia, and hepatosplenomegaly. Although most patients have a benign course, severe manifestations such as… read more here.
Keywords: onset still; adult onset; patients aosd; disease ... See more keywords
AOSD Endotypes based on immune cell profiles: patient stratification with hierarchical clustering analysis.
Sign Up to like & getrecommendations! Published in 2022 at "Rheumatology"
DOI: 10.1093/rheumatology/keac439
Abstract: OBJECTIVES This study aimed to analyse the immune cell profiles of adult-onset Still's disease (AOSD) and to stratify disease-associated endotypes. METHODS We included 95 cases of treatment-naïve patients with AOSD and 66 cases of healthy… read more here.
Keywords: cell profiles; immune cell; group; patients aosd ... See more keywords
SAT0533 ADULT ONSET STILLS DISEASE AND IDIOPATHIC RECURRENT PERICARDITIS: ARE THE MORE SIMILARITIES OR DIFFERENCES?
Sign Up to like & getrecommendations! Published in 2020 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2020-eular.4916
Abstract: Adult onset Stills disease (AOSD) and Idiopathic recurrent pericarditis (IRP) are currently considered auto-inflammatory diseases. Common features of these disorders are symptoms such as fever, leukocytosis, serositis, increased acute phase reactants.Diagnosis of IRP is based… read more here.
Keywords: onset stills; patients aosd; level; adult onset ... See more keywords
Human parvovirus B19 nonstructural protein NS1 activates NLRP3 inflammasome signaling in adult‑onset Still's disease.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular medicine reports"
DOI: 10.3892/mmr.2017.8275
Abstract: Dysregulation of inflammasomes serves a pathogenic role in autoinflammatory diseases (AIDs) and adult-onset Still's disease (AOSD) has been categorized as an AID. The present study investigated the expression of NLR family pyrin domain containing proteins… read more here.
Keywords: protein; onset still; adult onset; b19 ... See more keywords