Pharmacokinetics and Pharmacodynamics of Ceftolozane/Tazobactam in Critically Ill Patients With Augmented Renal Clearance.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of antimicrobial agents"
DOI: 10.1016/j.ijantimicag.2021.106299
Abstract: OBJECTIVE To determine whether established ceftolozane/tazobactam (C/T) dosing is adequate among patients with augmented renal clearance (ARC) and bacterial infection. METHODS ARC (creatinine clearance [CrCl] ≥130 mL/min) was confirmed by directly measured CrCl in 11… read more here.
Keywords: ceftolozane tazobactam; renal clearance; clearance; patients augmented ... See more keywords
Plasma trough concentration distribution and safety of high‐dose teicoplanin for patients with augmented renal clearance
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Pharmacy and Therapeutics"
DOI: 10.1111/jcpt.13700
Abstract: There are few reports on the distribution of the plasma trough concentration (Cmin) of teicoplanin in patients with augmented renal clearance (ARC) and on the safety of a high‐dose regimen (HD; 800 mg loading dose for… read more here.
Keywords: plasma trough; patients augmented; teicoplanin patients; renal clearance ... See more keywords
An HPLC-MS/MS method for determination of sulbactam in human plasma and its pharmacokinetic application in critically ill patients with augmented renal clearance.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of clinical pharmacology and therapeutics"
DOI: 10.5414/cp204339
Abstract: OBJECTIVE A simple, rapid, and specific method has been developed and validated to measure sulbactam in human plasma using high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). MATERIALS AND METHODS The pharmacokinetic characteristics of sulbactam in critically… read more here.
Keywords: ill patients; clearance; critically ill; patients augmented ... See more keywords