Evaluation of Plazomicin, Tigecycline, and Meropenem Pharmacodynamic Exposure against Carbapenem-Resistant Enterobacteriaceae in Patients with Bloodstream Infection or Hospital-Acquired/Ventilator-Associated Pneumonia from the CARE Study (ACHN-490-007)
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DOI: 10.1007/s40121-019-0251-4
Abstract: IntroductionCARE was a Phase 3, randomized study evaluating the efficacy and safety of plazomicin-based combination therapy compared with colistin-based combination therapy for the treatment of patients with bloodstream infections or hospital-acquired/ventilator-associated pneumonia due to carbapenem-resistant… read more here.
Keywords: patients bloodstream; tigecycline meropenem; exposure; meropenem ... See more keywords
The role of Geriatric Nutritional Risk Index in predicting adverse outcomes in patients with bloodstream infections: a retrospective study
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DOI: 10.1186/s12877-025-06387-6
Abstract: Nutritional deficiencies have been associated with the high prevalence of healthcare-associated infections (HAIs), which is particularly severe in elderly patients. The adverse effects of bloodstream infections (BSIs) in elderly patients are severe when they occur.… read more here.
Keywords: patients bloodstream; risk; gnri; bloodstream infections ... See more keywords
The Clinical Value of Systemic Immune Inflammatory Index in Predicting the Prognosis of Patients with Bloodstream Infection
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DOI: 10.2147/jir.s531272
Abstract: Introduction We analyzed the correlation between systemic immune inflammatory index (SII), systemic inflammatory response index (SIRI), systemic inflammatory index (AISI), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR) and mortality in patients with bloodstream… read more here.
Keywords: inflammatory index; patients bloodstream; bloodstream infection; inflammatory ... See more keywords
Value of CRP, PCT, and NLR in Prediction of Severity and Prognosis of Patients With Bloodstream Infections and Sepsis
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DOI: 10.3389/fsurg.2022.857218
Abstract: Objective To investigate the value of C-reactive protein (CRP), procalcitonin (PCT), and neutrophil to lymphocyte ratio (NLR) in assessing the severity of disease in patients with bloodstream infection and sepsis, and to analyze the relationship… read more here.
Keywords: patients bloodstream; prognosis patients; pct nlr; crp pct ... See more keywords
Epidemiological, Clinical and Microbiological Characteristics of Patients with Bloodstream Infections Due to Carbapenem-Resistant K. Pneumoniae in Southern Italy: A Multicentre Study
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DOI: 10.3390/antibiotics11050633
Abstract: Background: In the present study, our aim was to evaluate the clinical and microbiological characteristics of a cohort of patients with bloodstream infections (BSI) due to Carbapenem-Resistant Enterobacteriaceae (CRE) and investigate the independent predictors of… read more here.
Keywords: microbiological characteristics; carbapenem resistant; clinical microbiological; patients bloodstream ... See more keywords
Serum Cytokine Profile in Patients with Candidemia versus Bacteremia
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DOI: 10.3390/pathogens10101349
Abstract: Bloodstream Candida infections constitute a major threat for hospitalized patients in intensive care units and immunocompromised hosts. Certain serum cytokines play a decisive role in anti-microbial host defense. Cytokines may act as discriminatory biomarkers that… read more here.
Keywords: patients bloodstream; cytokine; serum cytokine; bloodstream candida ... See more keywords