Survival prediction in patients with colon adenocarcinoma via multiomics data integration using a deep learning algorithm
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20201482
Abstract: Abstract The present study proposed a deep learning (DL) algorithm to predict survival in patients with colon adenocarcinoma (COAD) based on multiomics integration. The survival-sensitive model was constructed using an autoencoder for DL implementation based… read more here.
Keywords: integration; model; learning algorithm; patients colon ... See more keywords
The incidence rate of allergic reactions induced by oxaliplatin is higher in patients with rectal cancer compared with colon cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Drug and chemical toxicology"
DOI: 10.1080/01480545.2023.2217700
Abstract: AIM To explore the diverse profiles of adverse reactions caused by oxaliplatin between colon and rectal cancer, we investigated the toxicity of oxaliplatin in patients with colon and rectal cancer. METHODS From January 2017 to… read more here.
Keywords: patients colon; patients rectal; colon cancer; rectal cancer ... See more keywords
Analytical validation of the Immunoscore and its associated prognostic value in patients with colon cancer
Sign Up to like & getrecommendations! Published in 2020 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2019-000272
Abstract: Background New and fully validated tests need to be brought into clinical practice to improve the estimation of recurrence risk in patients with colon cancer. The aim of this study was to assess the analytical… read more here.
Keywords: recurrence; prognostic value; colon cancer; cancer ... See more keywords
Low CPEB1 levels may predict the benefit of 5-fluorouracil treatment in patients with colon or stomach adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Gastrointestinal Oncology"
DOI: 10.21037/jgo-22-561
Abstract: Background For patients with colon or stomach adenocarcinoma, 5-fluorouracil (5-FU) is an essential component of systemic chemotherapy in the palliative and adjuvant settings. The post-transcriptional regulatory factor cytoplasmic polyadenylation element-binding protein 1 (CPEB1) has been… read more here.
Keywords: patients colon; cpeb1; stomach adenocarcinoma; colon stomach ... See more keywords
Impact of Nutritional Indices on the Survival Outcomes of Patients with Colorectal Cancer
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DOI: 10.2147/cmar.s243172
Abstract: Background The effect of preoperative nutritional status on the survival of patients with colorectal cancer is still unknown. The purpose of our study was to examine the impact of the prognostic nutritional index (PNI), prealbumin… read more here.
Keywords: rectal cancer; patients colorectal; cancer; colon rectal ... See more keywords
TPMT mRNA Expression: A Novel Prognostic Biomarker for Patients with Colon Cancer by Bioinformatics Analysis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of General Medicine"
DOI: 10.2147/ijgm.s338575
Abstract: Background To explore the clinicopathological significance and prognostic value of thiopurine methyltransferase (TPMT) in patients with colon cancer by bioinformatics analysis. Materials and Methods The clinicopathological information and TPMT expression data were downloaded from The… read more here.
Keywords: patients colon; colon cancer; cancer; tpmt mrna ... See more keywords
PFKFB3 overexpression in monocytes of patients with colon but not rectal cancer programs pro-tumor macrophages and is indicative for higher risk of tumor relapse
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1080501
Abstract: Introduction Circulating monocytes are main source for tumor-associated macrophages (TAMs) that control tumor growth, angiogenesis, metastasis and therapy resistance. We raised the questions how monocyte programming is affected by growing tumors localized in colon and… read more here.
Keywords: patients colon; colon rectal; analysis; rectal cancer ... See more keywords
Detection of circulating KRAS mutant DNA in extracellular vesicles using droplet digital PCR in patients with colon cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1067210
Abstract: Background Extracellular vesicles secreted by tumor cells contain double-stranded DNA called extracellular vesicle DNA (evDNA). EvDNA is genomic DNA that reflects cancer driver mutations. However, the significance of evDNA analysis in the diagnosis and surveillance… read more here.
Keywords: patients colon; dna; extracellular vesicles; colon cancer ... See more keywords
Clinical characteristics and prognosis of 196 Chinese patients with colon cancer
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Surgery"
DOI: 10.3389/fsurg.2022.1008149
Abstract: Aims To analyze the clinical characteristics and prognostic factors of Chinese patients with colon cancer. Methods A retrospective analysis of the records of patients with colon cancer underwent surgery between 2014 and 2017 was performed.… read more here.
Keywords: patients colon; surgery; colon cancer; analysis ... See more keywords
The Clinical Application of Immunohistochemical Expression of Notch4 Protein in Patients with Colon Adenocarcinoma
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DOI: 10.3390/ijms24087502
Abstract: The Notch signalling pathway is one of the most conserved and well-characterised pathways involved in cell fate decisions and the development of many diseases, including cancer. Among them, it is worth noting the Notch4 receptor… read more here.
Keywords: patients colon; clinical application; expression notch4; expression ... See more keywords
Complete Mesocolic Excision With Central Vascular Ligation in Comparison With Conventional Surgery for Patients With Colon Cancer – The Experiences at Two Centers
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Coloproctology"
DOI: 10.3393/ac.2017.08.05
Abstract: Purpose Revolutions have occurred over the last 3 decades in the management of patients with colorectal cancer. Most advances were in rectal cancer surgery, especially after the introduction of the total mesorectal excision (TME) by… read more here.
Keywords: cancer; cme group; patients colon; colon cancer ... See more keywords