A systemic review and metaanalysis of postoperative outcomes in urgent and elective bowel resection in patients with Crohn’s disease
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DOI: 10.1007/s00384-020-03786-6
Abstract: The study examined whether urgency of surgical intervention affects postoperative outcomes in patients with Crohn’s disease (CD) undergoing bowel resection. The review was conducted according to a predefined, published study protocol in Prospero which is… read more here.
Keywords: bowel resection; study; postoperative outcomes; patients crohn ... See more keywords
Association between preoperative biologic use and surgical morbidity in patients with Crohn’s disease
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DOI: 10.1007/s00384-022-04140-8
Abstract: We evaluated the influence of preoperative treatments with biologics on surgical morbidity in patients with Crohn’s disease (CD). We reviewed the surveillance data of patients with CD who underwent surgery between April 2018 and April… read more here.
Keywords: morbidity patients; morbidity; patients crohn; surgical morbidity ... See more keywords
Incidence of and Risk Factors for Free Bowel Perforation in Patients with Crohn’s Disease
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DOI: 10.1007/s10620-017-4539-5
Abstract: BackgroundIncidence of and risk factors for intestinal free perforation (FP) in patients with Crohn’s disease (CD) are not established.AimTo establish rate of and risk factors for FP in a large cohort of CD patients.MethodsMedical records… read more here.
Keywords: incidence; risk; risk factors; perforation patients ... See more keywords
Immunosuppressed Patients with Crohn’s Disease Are at Increased Risk of Postoperative Complications: Results from the ACS-NSQIP Database
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DOI: 10.1007/s11605-019-04186-0
Abstract: BackgroundThe impact of immunosuppressants on postoperative complications following colon resections for Crohn’s disease remains controversial. This study aimed to compare postoperative outcomes between immunosuppressed and immunocompetent patients with Crohn’s disease undergoing elective colon resection.MethodsAnalysis of… read more here.
Keywords: surgical site; disease; postoperative complications; database ... See more keywords
Adalimumab Reduces Extraintestinal Manifestations in Patients with Crohn’s Disease: A Pooled Analysis of 11 Clinical Studies
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DOI: 10.1007/s12325-018-0678-0
Abstract: IntroductionExtraintestinal manifestations (EIMs) in patients with Crohn’s disease (CD) are common and associated with additional morbidity. This study aimed to evaluate the effect of adalimumab therapy on EIM resolution and identify potential predictors of EIM… read more here.
Keywords: resolution; eim resolution; crohn disease; patients crohn ... See more keywords
Intestinal hypoperfusion in patients with Crohn's disease revealed by intraoperative indocyanine green fluorescence imaging
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DOI: 10.1016/j.amsu.2021.102402
Abstract: Background Anastomotic leakage has been reported as an independent risk factor for surgical recurrence at the anastomotic site in patients with Crohn's disease. An inadequate blood supply may contribute to this leakage. Real-time indocyanine green… read more here.
Keywords: colon; patients crohn; indocyanine green; crohn disease ... See more keywords
Long-term outcome of patients with Crohn's disease on home parenteral nutrition.
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DOI: 10.1016/j.nut.2020.110903
Abstract: OBJECTIVES In patients with Crohn's disease (CD) and intestinal failure, home parenteral nutrition (HPN) is a necessary lifesaving treatment. The aim of this study was to investigate the long-term outcomes of patients with CD after… read more here.
Keywords: parenteral nutrition; hpn; home parenteral; nutrition ... See more keywords
Discontinuation of Azathioprine could be considered in pediatric patients with Crohn’s disease who have sustained clinical and deep remission
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DOI: 10.1038/s41598-021-04304-6
Abstract: Few studies have demonstrated treatment strategies about the duration and cessation of medications in patients with Crohn’s disease (CD). We investigated factors affecting clinical relapse after infliximab (IFX) or azathioprine (AZA) withdrawal in pediatric patients… read more here.
Keywords: crohn disease; patients crohn; deep remission; relapse ... See more keywords
Development and Validation a Magnetic Resonance Index for Assessing Fistulas in Patients With Crohn's Disease.
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DOI: 10.1053/j.gastro.2019.07.027
Abstract: BACKGROUND & AIMS There is no validated magnetic resonance imaging (MRI) index for assessment of perianal fistulas in patients with Crohn's disease (CD). We developed and internally validated a new instrument. METHODS We used paired… read more here.
Keywords: index; magnetic resonance; disease; patients crohn ... See more keywords
Plasma levels of guanylins are reduced in patients with Crohn’s disease
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DOI: 10.1080/00365521.2020.1748224
Abstract: Abstract Background: Guanylin (GN) and uroguanylin (UGN) are endogenous ligands for the intestinal receptor guanylate cyclase C (GC-C), an important regulator of intestinal fluid homeostasis. Gene expression and protein levels of GN are suppressed in… read more here.
Keywords: plasma; guanylins reduced; levels guanylins; patients crohn ... See more keywords
Mortality in patients with Crohn's disease in Örebro, Sweden 1963-2010.
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DOI: 10.1080/00365521.2021.1991466
Abstract: BACKGROUND Some studies have suggested a reduced life expectancy in patients with Crohn's disease (CD) compared with the general population. The evidence, however, is inconsistent. AIMS Prompted by such studies, we studied survival of CD… read more here.
Keywords: age; disease; mortality; 1963 2010 ... See more keywords