Multiple biomarkers covering several pathways improve predictive ability for cognitive impairment among ischemic stroke patients with elevated blood pressure.
Sign Up to like & getrecommendations! Published in 2019 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2019.05.028
Abstract: BACKGROUND AND AIMS We aimed to evaluate the ability of multiple novel biomarkers representing several pathophysiological pathways to improve risk prediction of post-stroke cognitive impairment. METHODS We conducted a prospective multicenter study in 638 ischemic… read more here.
Keywords: ischemic stroke; patients elevated; cognitive impairment; impairment ... See more keywords
Extensive testing or focused testing of patients with elevated liver enzymes.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2016.09.017
Abstract: BACKGROUND & AIMS Many patients have elevated serum aminotransferases reflecting many underlying conditions, both common and rare. Clinicians generally apply one of two evaluative strategies: testing for all diseases at once (extensive) or just common… read more here.
Keywords: patients elevated; focused testing; liver enzymes; false positives ... See more keywords
PCSK9 Inhibition with alirocumab increases the catabolism of lipoprotein(a) particles in statin-treated patients with elevated lipoprotein(a).
Sign Up to like & getrecommendations! Published in 2020 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2020.154221
Abstract: BACKGROUND Lipoprotein(a) (Lp(a)) is a low-density lipoprotein (LDL) particle containing apolipoprotein(a) (apo(a)) covalently linked to apolipoprotein B-100 (apoB). Statin-treated patients with elevated Lp(a) have an increased risk of atherosclerotic cardiovascular disease (ASCVD). Recent trials show… read more here.
Keywords: patients elevated; statin treated; pcsk9 inhibition; treated patients ... See more keywords
Effect of Macrotroponin in a Cohort of Community Patients with Elevated Cardiac Troponin.
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DOI: 10.1093/clinchem/hvac118
Abstract: BACKGROUND Macrotroponin is an important cause of discrepancy between current high-sensitivity cardiac troponin (hs-cTn) assays, however, its clinical significance is unclear. This study examined the effects of macrotroponin and repeat testing by different hs-cTnI assays… read more here.
Keywords: cohort community; community patients; ctni; patients elevated ... See more keywords
Potent lipoprotein(a) lowering following apolipoprotein(a) antisense treatment reduces the pro-inflammatory activation of circulating monocytes in patients with elevated lipoprotein(a)
Sign Up to like & getrecommendations! Published in 2020 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehaa171
Abstract: Abstract Aims Elevated lipoprotein(a) [Lp(a)] is strongly associated with an increased cardiovascular disease (CVD) risk. We previously reported that pro-inflammatory activation of circulating monocytes is a potential mechanism by which Lp(a) mediates CVD. Since potent… read more here.
Keywords: inflammatory activation; patients elevated; treatment; circulating monocytes ... See more keywords
Characteristics and prognosis of patients with elevated triglycerides in acute myocardial infarction: observational data from a large database over a 17 years period
Sign Up to like & getrecommendations! Published in 2023 at "European Journal of Preventive Cardiology"
DOI: 10.1093/eurjpc/zwad125.141
Abstract: Type of funding sources: Private company. Main funding source(s): Amarin Corp. From a large database of a regional registry, we aimed to address the prevalence, characteristics and prognosis of patients with elevated triglycerides (TG) in… read more here.
Keywords: characteristics prognosis; database; patients elevated; large database ... See more keywords
Elevated preoperative CA125 is associated with poor survival in patients with metastatic colorectal cancer undergoing primary tumor resection: a retrospective cohort study
Sign Up to like & getrecommendations! Published in 2022 at "Gastroenterology Report"
DOI: 10.1093/gastro/goac020
Abstract: Abstract Background The impact of the preoperative carbohydrate antigen 125 (CA125) level on the survival of metastatic colorectal cancer (CRC) patients undergoing primary tumor resection (PTR) remains uncertain. The aim of this study was to… read more here.
Keywords: ca125; preoperative ca125; primary tumor; patients elevated ... See more keywords
Impact of bone marrow mononuclear cells therapy on left ventricular function in patients with ST-elevated myocardial infarction
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DOI: 10.1097/md.0000000000010359
Abstract: Background: Bone marrow mononuclear cell (BMMNC) therapy has been used as an adjunctive treatment in patients with ST-elevated myocardial infarction (STEMI). However, the therapeutic efficacy of this approach remains controversial. The present meta-analysis is aimed… read more here.
Keywords: patients elevated; myocardial infarction; marrow mononuclear; therapy ... See more keywords
Incompressible ankle arteries predict increased morbidity and mortality in patients with an elevated ankle brachial index.
Sign Up to like & getrecommendations! Published in 2022 at "Vascular"
DOI: 10.1177/17085381221127051
Abstract: OBJECTIVES Patients with an elevated ankle brachial index (ABI) > 1.3 have a high burden of disease and poorer outcome compared to patients with a lower ABI. Previously differences between patients with ABI > 1.3… read more here.
Keywords: ankle arteries; patients elevated; group; mortality ... See more keywords
Vascular surgery patients with elevated neutrophil-to-lymphocyte ratios have downregulated neutrophil complement RNA expression
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2022008419
Abstract: Key Points • Changes in neutrophils is the dynamic factor altering neutrophil-to-lymphocyte ratios in patients who undergo elective vascular surgery.• Patients with elevated neutrophil-to-lymphocyte ratios are associated with reduced expression of complement genes in neutrophils. read more here.
Keywords: surgery patients; vascular surgery; elevated neutrophil; patients elevated ... See more keywords
Long-term outcomes and propensity score matching analysis: rectal cancer resection for patients with elevated preoperative risk
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.13827
Abstract: BACKGROUND It is still controversial about the treatment strategy for rectal cancer patients with elevated operative risk and elder rectal cancer patients. METHODS This study presented a retrospective single center experience in rectal cancer proctectomy… read more here.
Keywords: risk; patients elevated; rectal cancer; cancer ... See more keywords