Prolonged infusion of linezolid is associated with improved pharmacokinetic/pharmacodynamic (PK/PD) profiles in patients with external ventricular drains
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DOI: 10.1007/s00228-020-02978-x
Abstract: Objective We previously investigated the pharmacokinetic and pharmacodynamic (PK/PD) parameters of routine linezolid infusions (1 h) in patients with external ventricular drains (EVD). The aim of the study was to determine whether extended linezolid infusions… read more here.
Keywords: infusion; prolonged infusion; csf; linezolid infusions ... See more keywords
Physiological Responses to In-Bed Cycle Ergometry Treatment in Intensive Care Unit Patients with External Ventricular Drainage
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DOI: 10.1007/s12028-021-01204-5
Abstract: Evidence suggests that early physical activity can be accomplished safely in the neurocritical care unit (NCCU); however, many NCCU patients are often maintained in a state of inactivity due to impaired consciousness, sensorimotor deficits, and… read more here.
Keywords: care unit; neurocritical care; cycle ergometry; patients external ... See more keywords
Plasma and Cerebrospinal Fluid Population Pharmacokinetics of Vancomycin in Patients with External Ventricular Drain
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DOI: 10.1128/aac.00241-23
Abstract: Vancomycin is a commonly used antibacterial agent in patients with primary central nervous system (CNS) infection. This study aims to examine predictors of vancomycin penetration into cerebrospinal fluid (CSF) in patients with external ventricular drainage… read more here.
Keywords: vancomycin; csf; infection; cerebrospinal fluid ... See more keywords