The different relations of PCSK9 and Lp(a) to the presence and severity of atherosclerotic lesions in patients with familial hypercholesterolemia.
Sign Up to like & getrecommendations! Published in 2018 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2018.07.030
Abstract: BACKGROUND AND AIMS The relation of lipoprotein (a) [Lp(a)] and proprotein convertase substilisin/kexin type 9 (PCSK9) levels to coronary artery disease (CAD) has been well established in the general population, while little is known about… read more here.
Keywords: presence severity; patients familial; pcsk9 presence; severity ... See more keywords
Economic evaluation of lipid lowering with PCSK9 inhibitors in patients with familial hypercholesterolemia: Methodological aspects.
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DOI: 10.1016/j.atherosclerosis.2019.06.900
Abstract: BACKGROUND AND AIMS Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors have proved to reduce low density lipoprotein cholesterol levels in numerous clinical trials. In two large clinical trials, PCSK9 inhibitor treatment reduced the risk of… read more here.
Keywords: pcsk9 inhibitors; patients familial; cost effective; familial hypercholesterolemia ... See more keywords
Next-generation sequencing in patients with familial FSGS: first report of collagen gene mutations in Tunisian patients.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of human genetics"
DOI: 10.1038/s10038-021-00912-2
Abstract: Focal segmental glomerulosclerosis (FSGS) is a histological lesion with many causes, including inherited genetic defects, with significant proteinuria being the predominant clinical finding at presentation. FSGS is considered as a podocyte disease due to the… read more here.
Keywords: patients familial; sequencing patients; gene; next generation ... See more keywords
Efficacy and safety of intensive downstaging polypectomy (IDP) for multiple duodenal adenomas in patients with familial adenomatous polyposis: a prospective cohort study
Sign Up to like & getrecommendations! Published in 2022 at "Endoscopy"
DOI: 10.1055/a-1983-5963
Abstract: BACKGROUND AND STUDY AIMS Patients with familial adenomatous polyposis (FAP) risk developing multiple duodenal adenomas (MDAs), leading to duodenal cancer and death. We investigated the safety and efficacy of intensive endoscopic intervention for MDAs integrated… read more here.
Keywords: adenomatous polyposis; duodenal adenomas; patients familial; multiple duodenal ... See more keywords
The assessment of tocilizumab therapy on recurrent attacks of patients with familial Mediterranean fever: A retrospective study of 15 patients
Sign Up to like & getrecommendations! Published in 2020 at "Modern Rheumatology"
DOI: 10.1080/14397595.2019.1709258
Abstract: Abstract Aim Interleukin-6 receptor antagonist, tocilizumab (TCZ), is known to be effective in the treatment of amyloidosis in patients with familial Mediterranean fever (FMF). But there are limited data about the effect of TCZ on… read more here.
Keywords: frequency; tcz; patients familial; study ... See more keywords
How is gut microbiome of patients with familial adenomatous polyposis different from healthy people?
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000032194
Abstract: The gut microbiome has been increasingly suggested as an underlying cause of various human diseases. In this study, we hypothesized that the gut microbiomes of patients with familial adenomatous polyposis (FAP) are different from those… read more here.
Keywords: patients fap; adenomatous polyposis; healthy people; patients familial ... See more keywords
Metformin combined with endoscopic therapy in patients with familial polyposis associated with carcinoma: A case report
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DOI: 10.1097/md.0000000000032408
Abstract: Rationale: Familial adenomatous polyposis (FAP) is an autosomal dominant genetic disease, with a very high cancer rate. At present, endoscopic resection of polyps ≥ 1 cm is often chosen for patients with non-cancerous polyps who are unwilling to… read more here.
Keywords: combined endoscopic; metformin combined; patients familial; endoscopic therapy ... See more keywords
Colchicine resistance: Associated factors and its effect on health‐related quality of life in patients with familial Mediterranean fever
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Rheumatic Diseases"
DOI: 10.1111/1756-185x.14407
Abstract: To determine the factors associated with colchicine resistance and the effect of colchicine resistance on health‐related quality of life (QoL) in patients with familial Mediterranean fever (FMF). read more here.
Keywords: colchicine resistance; resistance; patients familial; quality life ... See more keywords
Long‐term results of kidney transplantation in patients with familial mediterranean fever
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DOI: 10.1111/ctr.14888
Abstract: Long‐term kidney transplantation (KT) results in patients with familial Mediterranean fever (FMF)‐related amyloidosis are not well studied. This study reviewed the long‐term survival outcomes of FMF patients who underwent KT. read more here.
Keywords: long term; familial mediterranean; term; kidney transplantation ... See more keywords
The red blood cell as a mediator of endothelial dysfunction in patients with familial hypercholesterolemia and dyslipidemia
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Internal Medicine"
DOI: 10.1111/joim.13580
Abstract: Patients with familial hypercholesterolemia (FH) display high levels of low‐density lipoprotein cholesterol (LDL‐c), endothelial dysfunction, and increased risk of premature atherosclerosis. We have previously shown that red blood cells (RBCs) from patients with type 2… read more here.
Keywords: red blood; dysfunction; patients familial; endothelial dysfunction ... See more keywords
P12 Exploring the value of computed tomography coronary angiography in guiding management of asymptomatic patients with familial hypercholesterolaemia
Sign Up to like & getrecommendations! Published in 2020 at "Heart"
DOI: 10.1136/heartjnl-2020-bsci.25
Abstract: Introduction Computed tomography coronary angiography (CTCA) is increasingly requested in asymptomatic patients with familial hypercholesterolaemia (FH) to risk stratify and determine cholesterol management strategies. Currently there is no consensus regarding the value of calcium scoring… read more here.
Keywords: tomography coronary; management; asymptomatic patients; coronary angiography ... See more keywords