Small molecule tyrosine kinase inhibitors in glioblastoma
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DOI: 10.1007/s12272-020-01232-3
Abstract: Glioblastoma (GBM) is the most common malignant primary brain tumor, with poor survival despite treatment with surgery, radiotherapy, and chemotherapy with temozolomide. Little progress has been made over the last two decades, and there remain… read more here.
Keywords: kinase inhibitors; molecule; patients gbm; small molecule ... See more keywords
Significance and Prognostic Value of The Coagulation Profile in Patients with Glioblastoma: Implications for Personalized Therapy.
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DOI: 10.1016/j.wneu.2018.09.177
Abstract: BACKGROUND Coagulation is an important aspect of the vascular microenvironment in which brain tumors evolve. Patients with tumor often show aberrant coagulation and fibrinolysis activation. In particular, glioblastoma (GBM), the most aggressive primary brain tumor,… read more here.
Keywords: coagulation; patients gbm; significance; coagulation profile ... See more keywords
Characteristics and management of tumor treating fields-related dermatological complications in patients with glioblastoma
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DOI: 10.1097/md.0000000000033830
Abstract: Tumor treating fields (TTFields) is a novel approved modality for the treatment of glioblastoma (GBM) exhibiting a satisfactory effect. Although TTFields has shown considerable safety for the normal brain, dermatological adverse events (DAEs) often occur… read more here.
Keywords: management; treating fields; characteristics management; patients gbm ... See more keywords
Prognostic model for predicting overall survival in patients with glioblastoma: an analysis based on the SEER database
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Investigative Medicine"
DOI: 10.1177/10815589221147153
Abstract: Predicting the prognosis of glioblastoma (GBM) has always been important for improving survival. An understanding of the prognostic factors for patients with GBM can help guide treatment. Herein, we aimed to construct a prognostic model… read more here.
Keywords: survival; model predicting; model; cohort ... See more keywords
Early Diagnosis and Surgical Intervention Within 3 Weeks From Symptom Onset Are Associated With Prolonged Survival of Patients With Glioblastoma
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DOI: 10.1227/neu.0000000000002096
Abstract: BACKGROUND: Glioblastoma (GBM) is a rapidly growing and most life-threatening malignant brain tumor. The significance of early treatment to the clinical outcomes of patients with GBM is unclear. OBJECTIVE: To determine whether early diagnosis and… read more here.
Keywords: diagnosis; surgery; survival; within weeks ... See more keywords
Mesothelin as a novel biomarker and immunotherapeutic target in human glioblastoma
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DOI: 10.18632/oncotarget.20303
Abstract: Glioblastoma multiforme (GBM) presents the most malignant form of glioma, with a 5-year survival rate below 3% despite standard therapy. Novel immune-based therapies in improving treatment outcomes in GBM are therefore warranted. Several molecularly defined… read more here.
Keywords: patients gbm; glioblastoma; target; mesothelin ... See more keywords